AB2256
Anti-GABA B Receptor R1 Antibody
serum, from guinea pig
Sinonimo/i:
GABA-B receptor, GABA-B receptor 1, GABAB, subunit 1c, gamma-aminobutyric acid (GABA) B receptor 1, gamma-aminobutyric acid B receptor 1, seven transmembrane helix receptor
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About This Item
Codice UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Prodotti consigliati
Origine biologica
guinea pig
Livello qualitativo
Forma dell’anticorpo
serum
Tipo di anticorpo
primary antibodies
Clone
polyclonal
Reattività contro le specie
mouse, human, rat
tecniche
immunohistochemistry: suitable
western blot: suitable
N° accesso NCBI
N° accesso UniProt
Condizioni di spedizione
wet ice
modifica post-traduzionali bersaglio
unmodified
Informazioni sul gene
mouse ... Gabbr1(54393)
Descrizione generale
Gamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the mammalian central nervous system. GABA exerts its effects through ionotropic [GABA(A/C)] receptors, to produce fast synaptic inhibition, and metabotropic [GABA(B)] receptors, to produce slow, prolonged inhibitory signals. The GABA(B) receptor consists of a heterodimer of two related 7-transmembrane receptors, GABA(B) receptor 1 and GABA(B) receptor 2. The GABA(B) receptor 1 gene is mapped to chromosome 6p21.3 within the HLA class I region close to the HLA-F gene. Susceptibility loci for multiple sclerosis, epilepsy, and schizophrenia have also been mapped in this region. Alternative splicing of this gene generates 4 transcript variants.
Specificità
Cat. # AB2256 recognizes GABA B Receptor R1 (GABA B R1)
Reactivity with other species has not been determined.
Immunogeno
Epitope: C-Terminus
interaction w/ ATF4
interaction w/ ATF4
Recombinant peptide (aa 972-991: PSEPPDRLSCDGSRVHLLYK)
Applicazioni
Detect GABA B Receptor R1 using this Anti-GABA B Receptor R1 Antibody validated for use in WB, IH.
Immunohistochemistry: Working dilution of 1:3,000 in free floating mouse brain tissue.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Neurotransmitters & Receptors
Neurotransmitters & Receptors
Qualità
Western Blotting: 1:1,000 dilution from a previous lot detected GABA B R1 on 10µg of rat brain lysate.
Descrizione del bersaglio
~100-105 kDa
Stato fisico
GST-Depleted Sera with 0.05% NaN3.
Stoccaggio e stabilità
Stable for 1 year at -20ºC from date of receipt.
Risultati analitici
Control
Rat brain lysates
Rat brain lysates
Esclusione di responsabilità
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Codice della classe di stoccaggio
12 - Non Combustible Liquids
Classe di pericolosità dell'acqua (WGK)
WGK 1
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
Certificati d'analisi (COA)
Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.
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Aline M Davis et al.
The Journal of comparative neurology, 449(3), 270-280 (2002-07-13)
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