8.08261

Trifluoroacetic anhydride

for synthesis

• Sinonimo/i: Trifluoroacetic anhydride, Bis(trifluoroacetic) anhydride, TFAA
• Formula condensata: (CF₃CO)₂O
• Numero CAS: 407-25-0
• Peso molecolare: 210.03
• Numero MDL: MFCD00000416
• Codice UNSPSC: 12352106
• Numero indice EU: 206-982-9

Proprietà

• Tensione di vapore: 405 hPa ( 20 °C)
• Livello qualitativo: 200
• Saggio: ≥99.0% (GC)
• Forma fisica: liquid
• P. eboll.: 40 °C/1013 hPa
• Punto di fusione: -65 °C
• Densità: 1.51 g/cm³ at 20 °C
• Temperatura di conservazione: 2-30°C
• InChI: 1S/C4F6O3/c5-3(6,7)1(11)13-2(12)4(8,9)10; QAEDZJGFFMLHHQ-UHFFFAOYSA-N

Descrizione

Applicazioni

• Cascade Rearrangement: Nitro Group-Participating Syntheses of 1,2,5-Thiadiazoles and 1,2,4-Thiadiazolones.: This study explores the role of trifluoroacetic anhydride in the synthesis of thiadiazoles and thiadiazolones via a nitro group-participating cascade rearrangement, highlighting its utility in organic synthesis (Li et al., 2024).


• Copper Loading-Controlled Selective Synthesis of 2,5-Bis(trifluoromethyl) and Monotrifluoromethyl-Substituted Oxazoles.: This research demonstrates the selective synthesis of trifluoromethyl-substituted oxazoles using trifluoroacetic anhydride, showcasing its versatility in controlling copper loading during reactions (Wu et al., 2024).


• Wood Esterification by Fatty Acids Using Trifluoroacetic Anhydride as an Impelling Agent and Its Application for the Synthesis of a New Bioplastic.: The study presents a novel method for wood esterification using trifluoroacetic anhydride, facilitating the development of new bioplastic materials (Sejati et al., 2023).


• Synthesis of alpha-Seleno Boronates via Diboration of Carbonyl Compounds.: This paper details the synthesis of alpha-seleno boronates using trifluoroacetic anhydride in the diboration of carbonyl compounds, emphasizing its reactivity and selectivity in chemical transformations (Paul et al., 2023).


• Regioselective Synthesis of 3-Nitroindoles Under Non-Acidic and Non-Metallic Conditions.: The research highlights the use of trifluoroacetic anhydride in the regioselective synthesis of 3-nitroindoles, demonstrating its efficiency under non-acidic and non-metallic conditions (Zhang et al., 2023).

Risultati analitici

Assay (GC, area%): ≥ 99.0 % (a/a)
Density (d 20 °C/ 4 °C): 1.509 - 1.512
Identity (IR): passes test

Informazioni sulla sicurezza

• Pittogrammi: GHS05,GHS07
• Avvertenze: Danger
• Indicazioni di pericolo: H314 - H332 - H412
• Consigli di prudenza: P261 - P273 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Classi di pericolo: Acute Tox. 4 Inhalation - Aquatic Chronic 3 - Eye Dam. 1 - Skin Corr. 1A
• Rischi supp: EUH014
• Codice della classe di stoccaggio: 8B - Non-combustible, corrosive hazardous materials
• Classe di pericolosità dell'acqua (WGK): WGK 2