459618

Okadaic Acid potassium salt

≥95% (HPLC), solid, protein phosphatase 2A and protein phosphatase 1 inhibitor, Calbiochem^®

• Sinonimo/i: Okadaic Acid, Potassium Salt
• Formula empirica (notazione di Hill): C₄₄H₆₇O₁₃ · K
• Numero CAS: 155751-72-7
• Peso molecolare: 843.09
• Numero MDL: MFCD00214356
• Codice UNSPSC: 12352106
• NACRES: NA.77

Proprietà

• product name: Okadaic Acid, Potassium Salt, Water-soluble analog of Okadaic Acid. Inhibits protein phosphatases 1 and 2A.
• Livello qualitativo: 100
• Saggio: ≥95% (HPLC)
• Forma fisica: solid
• Produttore/marchio commerciale: Calbiochem^®
• Condizioni di stoccaggio: OK to freeze; protect from light
• Colore: white
• Solubilità: water: 1 mg/mL; DMSO: 20 mg/mL; ethanol: 20 mg/mL
• Condizioni di spedizione: ambient
• Temperatura di conservazione: −20°C
• InChI: 1S/C44H68O13.K/c1-25-21-34(55-44(23-25)35(46)12-11-31(54-44)24-41(6,50)40(48)49)26(2)9-10-30-14-18-43(53-30)19-15-33-39(57-43)36(47)29(5)38(52-33)32(45)22-28(4)37-27(3)13-17-42(56-37)16-7-8-20-51-42;/h9-10,23,26-28,30-39,45-47,50H,5,7-8,11-22,24H2,1-4,6H3,(H,48,49);/q;+1/p-1; UXRQUXBFVICHQJ-UHFFFAOYSA-M

Descrizione

Descrizione generale

Water-soluble analog of Okadaic Acid (Cat. No. 495604). Inhibits protein phosphatases 1 and 2A.

Water-soluble analog of Okadaic Acid (Cat. No. 495604). Inhibits protein phosphatases 1 and 2A.

Azioni biochim/fisiol

Cell permeable: no

Primary Target
PP1, PP2

Product does not compete with ATP.

Reversible: no

Target IC₅₀: 10-15 nM, 0.1 nM, against protein phosphatase 1 and protein phosphatase 2A, respectively

Attenzione

Toxicity: Toxic (F)

Ricostituzione

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.

Altre note

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.

Gjertsen, B.T., et al. 1994. J. Cell Sci.107, 3363.
Kiguchi, K., et al. 1994. Cell Growth Differ.5, 995.
Ohaka, Y., et al. 1993. Biochem. Biophys. Res. Commun.197, 916.
Gopalakrishna, R., et al. 1992. Biochem. Biophys. Res. Commun.189, 950.
Kreienbuhl, P., et al. 1992. Blood80, 2911.
Nomura, M., et al. 1992. Biochemistry31, 11915.
Song, Q., et al. 1992. J. Cell Physiol.153, 550.
Tada, Y., et al. 1992. Immunopharmacol.24, 17.

Note legali

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Informazioni sulla sicurezza

• Pittogrammi: GHS06
• Avvertenze: Danger
• Indicazioni di pericolo: H301 + H311 + H331,H315
• Consigli di prudenza: P261 - P264 - P280 - P301 + P310 - P302 + P352 + P312 - P304 + P340 + P311
• Classi di pericolo: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Skin Irrit. 2
• Codice della classe di stoccaggio: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable