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Merck
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Documenti fondamentali

428017

Sigma-Aldrich

Anti-Lamp1 Mouse mAb (LY1C6)

liquid, clone LY1C6, Calbiochem®

Sinonimo/i:

Anti-Lysosome-Associated Membrane Protein 1

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About This Item

Codice UNSPSC:
12352203
NACRES:
NA.41

Origine biologica

mouse

Livello qualitativo

100

Forma dell’anticorpo

purified antibody

Tipo di anticorpo

primary antibodies

Clone

LY1C6, monoclonal

Forma fisica

liquid

contiene

≤0.09% sodium azide as preservative

Reattività contro le specie

rat

Produttore/marchio commerciale

Calbiochem®

Condizioni di stoccaggio

OK to freeze
avoid repeated freeze/thaw cycles

Isotipo

IgG1

Condizioni di spedizione

wet ice

Temperatura di conservazione

−20°C

modifica post-traduzionali bersaglio

unmodified

Informazioni sul gene

rat ... Lamp1(25328)

Descrizione generale

Protein G purified mouse monoclonal antibody. Recognizes the ~120 kDa Lamp1 protein.
Recognizes the ~120 kDa Lamp1 protein.
This Anti-Lamp1 Mouse mAb (LY1C6) is validated for use in Immunoblotting, Immunocytochemistry, Immunofluorescence, Immunoprecipitation for the detection of Lamp1.

Immunogeno

Rat
rat liver lysosomal membranes

Applicazioni

Immunoblotting (1 µg/ml, chemiluminescence)

Immunocytochemistry (1:100)

Immunofluorescence (see comments)

Immunoprecipitation (see comments)

Confezionamento

Please refer to vial label for lot-specific concentration.

Attenzione

Toxicity: Standard Handling (A)

Stato fisico

In PBS containing 50% glycerol, pH 7.2.

Ricostituzione

Following initial thaw, aliquot and freeze (-20°C).

Risultati analitici

Positive Control
CHO-K1 cells

Altre note

Kannan, K. et al. 1996. Cell Immunol.171, 10.
Rohrer, J., et al. 1996. J. Cell Biol. 132, 565.
Howe et al. 1988. PNAS85, 7577.
Lewis et al. 1985. J. Cell Biol.100, 1839.
This antibody has also been reported to work for immunofluorescence and immunoprecipitation. Antibody should be titrated for optimal results in individual systems.

Note legali

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

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Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Arvind Chhabra et al.
European journal of immunology, 34(10), 2824-2833 (2004-09-16)
Dendritic cells (DC) capture antigens from apoptotic and/or necrotic tumor cells and cross-present them to T cells, and various ways of delivering tumor antigens to DC in vitro and in vivo are being pursued. Since fusions of antigenic proteins with
Vanessa Ginet et al.
The American journal of pathology, 175(5), 1962-1974 (2009-10-10)
The multiplicity of cell death mechanisms induced by neonatal hypoxia-ischemia makes neuroprotective treatment against neonatal asphyxia more difficult to achieve. Whereas the roles of apoptosis and necrosis in such conditions have been studied intensively, the implication of autophagic cell death
Raymond E Hulse et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 28(47), 12199-12211 (2008-11-21)
In brain, monomeric immunoglobin G (IgG) is regarded as quiescent and only poised to initiate potentially injurious inflammatory reactions via immune complex formation associated with phagocytosis and tumor necrosis factor alpha (TNF-alpha) production in response to disease. Using rat hippocampal
Julien Puyal et al.
Annals of neurology, 66(3), 378-389 (2009-06-25)
To evaluate the contributions of autophagic, necrotic, and apoptotic cell death mechanisms after neonatal cerebral ischemia and hence define the most appropriate neuroprotective approach for postischemic therapy. Rats were exposed to transient focal cerebral ischemia on postnatal day 12. Some
Vanessa Ginet et al.
Autophagy, 10(5), 846-860 (2014-03-29)
Neuronal autophagy is increased in numerous excitotoxic conditions including neonatal cerebral hypoxia-ischemia (HI). However, the role of this HI-induced autophagy remains unclear. To clarify this role we established an in vitro model of excitotoxicity combining kainate treatment (Ka, 30 µM)

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