182750

ASB-14

A zwitterionic amidosulfobetaine detergent useful for solubilizing proteins visualized by 2D-electrophoresis.

• Sinonimo/i: ASB-14
• Formula empirica (notazione di Hill): C₂₂H₄₆N₂O₄S
• Peso molecolare: 434.68
• Codice UNSPSC: 12161902
• NACRES: NA.21

Proprietà

• Livello qualitativo: 100
• Saggio: ≥97% (HPLC)
• Forma fisica: solid
• Produttore/marchio commerciale: Calbiochem^®
• Condizioni di stoccaggio: OK to freeze; desiccated (hygroscopic)
• Colore: white to off-white
• Solubilità: water: 50 mg/mL
• Condizioni di spedizione: ambient
• Temperatura di conservazione: 10-30°C

Descrizione

Descrizione generale

A zwitterionic amidosulfobetaine detergent that exhibits better protein extraction properties than CHAPS.

A zwitterionic amidosulfobetaine detergent useful for solubilizing proteins visualized by 2D-electrophoresis. The increased solubilization produced by this detergent enables the identification of previously undetected membrane proteins.

Applicazioni

• Effect of bovine pericardial extracellular matrix scaffold niche on seeded human mesenchymal stem cell function.: This paper explores the influence of the bovine pericardial extracellular matrix on human mesenchymal stem cells, with ASB-14 used to modulate cellular responses. The research contributes to advancements in scaffold-based tissue engineering (Liu et al., 2016).


• In vivo xenogeneic scaffold fate is determined by residual antigenicity and extracellular matrix preservation.: Investigating the fate of xenogeneic scaffolds in vivo, this study shows that ASB-14 helps maintain extracellular matrix integrity and reduce antigenicity, which is critical for successful scaffold integration and function in tissue engineering (Wong et al., 2016).

Attenzione

Toxicity: Irritant (B)

Ricostituzione

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 year at -20°C.

Altre note

Carroll, J., et al. J. Biol. Chem.277, 50311.
Herbert, B. 1999. Electrophoresis20, 660.
Chevallet, M. et al. 1998. Electrophoresis 19, 1901.

Note legali

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable