1.00631

Salicylic acid

EMPROVE^® ESSENTIAL Ph Eur,BP,USP

• Sinonimo/i: Salicylic acid, 2-Hydroxybenzoic acid
• Formula empirica (notazione di Hill): C₇H₆O₃
• Numero CAS: 69-72-7
• Peso molecolare: 138.12
• Numero MDL: MFCD00002439
• Codice UNSPSC: 12352106
• Numero indice EU: 200-712-3

Proprietà

• agenzia: BP; Ph. Eur.; USP
• Livello qualitativo: 500
• Tensione di vapore: <1 hPa ( 100 °C)
• Nome Commerciale: EMPROVE^® ESSENTIAL
• Saggio: 98.0-102.0% dry basis (HPLC)
• Stato: solid
• Temp. autoaccensione: 500 °C
• Potenza: 1250-1580 mg/kg LD₅₀, oral (Rat); >2000 mg/kg LD₅₀, skin (Rat)
• tecniche: API processing | cocrystal formation: suitable; API processing | salt formation: suitable
• pH: 2.4 ( in H₂O, saturated solution)
• P. ebollizione: 211 °C/1013 hPa
• Punto di fusione: 157-159 °C
• Temp. transizione: flash point 157 °C
• Solubilità: 2 g/L
• Densità: 1.443 g/cm³ at 20 °C
• Densità bulk: 400‑500 kg/m³
• Anioni in tracce: chloride (Cl^-): ≤0.0100%; sulfate (SO₄^2-): ≤0.0200%
• applicazioni: liquid formulation; pharmaceutical
• Temperatura di conservazione: 15-25°C
• Stringa SMILE: [O-]c1c(cccc1)C(=O)O.[H+]
• InChI: 1S/C7H6O3/c8-6-4-2-1-3-5(6)7(9)10/h1-4,8H,(H,9,10); YGSDEFSMJLZEOE-UHFFFAOYSA-N

Descrizione

Descrizione generale

We offer a range of high quality critical raw materials, solvents and reagents plus the documentation and expertise to meet stringent regulatory requirements. In addition to our comprehensive portfolio, we also offer custom manufacturing services to meet your exact needs. As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Applicazioni

Salicylic acid is used in dermatological medicine for skin exfoliating and acne. Salicylic acid Emprove^® Essential is suitable for pharmaceutical applications.

Note legali

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Informazioni sulla sicurezza

• Pittogrammi: GHS08,GHS05,GHS07
• Avvertenze: Danger
• Indicazioni di pericolo: H302,H318,H361d
• Consigli di prudenza: P202 - P264 - P280 - P301 + P312 - P305 + P351 + P338 - P308 + P313
• Classi di pericolo: Acute Tox. 4 Oral - Eye Dam. 1 - Repr. 2
• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): 314.6 °F - closed cup
• Punto d’infiammabilità (°C): 157 °C - closed cup