06-1005

Anti-TRIC-A Antibody

from rabbit, purified by affinity chromatography

• Sinonimo/i: transmembrane protein 38A, trimeric intracellular cation channel type A, Tmem38a, NET1
• Codice UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Proprietà

• Origine biologica: rabbit
• Livello qualitativo: 100
• Forma dell’anticorpo: affinity isolated antibody
• Tipo di anticorpo: primary antibodies
• Clone: polyclonal
• Purificato mediante: affinity chromatography
• Reattività contro le specie: human, mouse, rat
• Reattività contro le specie (prevista in base all’omologia): chimpanzee (based on 100% sequence homology)
• tecniche: immunocytochemistry: suitable; immunohistochemistry: suitable; western blot: suitable
• N° accesso NCBI: NP_076979.1
• N° accesso UniProt: Q9H6F2
• Condizioni di spedizione: wet ice
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: human ... TMEM38A(79041)

Descrizione

Descrizione generale

TRIC-A (trimeric intracellular cation channel type A), also known as Tmem38A, and sometimes NET1, is one of a number of TRIC channel subtypes that are believed to function as a Ca2+ counter-ion channel. TRIC-A is highly expressed in excitable cells and seems to work in coordination with Ca2+ release to balance transient negative potential. TRIC-A is located on the sarcoplasmic reticulum (SR) and is thought to be regulated by trans-membrane voltage. TRIC-A deficiency may lead to an abundance of Ca2+ and cause volatility in Ca2+ movement across the SR membrane.

Specificità

This antibody recognizes the cytoplasmic domain of TRIC-A.

Immunogeno

Epitope: Cytoplasmic domain

KLH-conjugated linear peptide corresponding to the cytoplasmic domain of human TRIC-A.

Applicazioni

Anti-TRIC-A Antibody detects level of TRIC-A & has been published & validated for use in WB, IH & IC.

Immunohistochemistry Analysis: A representative lot was used by an independent laboratory in IH. (Wilkie, G.S., et al. (2011). Mol Cell Proteomics. 10(1):M110.003129-1).

Immunocytochemistry Analysis: A representative lot was used by an independent laboratory in IC. (Wilkie, G.S., et al. (2011). Mol Cell Proteomics. 10(1):M110.003129-1).

Research Category
Epigenetics & Nuclear Function

Research Sub Category
GPCR, cAMP/cGMP & Calcium Signaling

Qualità

Evaluated by Western Blot in human fetal skeletal muscle tissue lysate.

Western Blot Analysis: 1 µg/mL of this antibody detected TRIC-A on 10 µg of human fetal skeletal muscle tissue lysate.

Descrizione del bersaglio

~33 kDa observed

Stato fisico

Affinity purified

Purified rabbit polyclonal in PBS containing 0.05% sodium azide.

Stoccaggio e stabilità

Stable for 1 year at 2-8°C from date of receipt.

Risultati analitici

Control
Human fetal skeletal muscle tissue lysate.

Altre note

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 12 - Non Combustible Liquids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable