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Merck
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Key Documents

05-446

Sigma-Aldrich

Anti-p75NTR (Neurotrophin Receptor) Antibody, clone ME20.4

clone A16/17, Upstate®, from mouse

Sinonimo/i:

p75 Low Affinity Neurotrophin Receptor, NGFR

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About This Item

Codice UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Origine biologica

mouse

Livello qualitativo

100

Forma dell’anticorpo

purified immunoglobulin

Tipo di anticorpo

primary antibodies

Clone

A16/17, monoclonal

Reattività contro le specie

monkey, human

Produttore/marchio commerciale

Upstate®

tecniche

immunohistochemistry: suitable
immunoprecipitation (IP): suitable
neutralization: suitable
western blot: suitable

Isotipo

IgG1

N° accesso NCBI

NM_002507

N° accesso UniProt

P08138

Condizioni di spedizione

dry ice

modifica post-traduzionali bersaglio

unmodified

Informazioni sul gene

human ... NGFR(4804)

Specificità

low affinity p75NTR

Immunogeno

Human melanoma cell line WM245.

Applicazioni

Anti-p75NTR (Neurotrophin Receptor) Antibody, clone ME20.4 detects level of p75NTR (Neurotrophin Receptor) & has been published & validated for use in IP, WB, IH, NEUT.
Research Category
Neuroscience
Research Sub Category
Kinases & Phosphatases

Neurodegenerative Diseases

Qualità

routinely evaluated by immunoblot on RIPA lysates from HS294T cells

Descrizione del bersaglio

69kDa

Linkage

Replaces: 04-1111

Stato fisico

0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%
Format: Purified
Protein G Chromatography

Stoccaggio e stabilità

2 years at -20°C

Altre note

Due to license agreement restrictions, this product cannot be purchased for resale.

Note legali

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Certificati d'analisi (COA)

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Low-affinity nerve growth factor receptor immunoreactivity in the human urinary bladder.
Wakabayashi, Y, et al.
Neuroscience Letters, 186, 9-12 (1995)
Immuno-electron microscopy characterization of human bone marrow stromal cells with anti-NGFR antibodies.
Caneva, L, et al.
Blood Cells, Molecules and Diseases, 21, 73-85 (1995)
J Du et al.
The Journal of cell biology, 150(6), 1423-1434 (2000-09-20)
Brain-derived neurotrophic factor (BDNF) has been shown to regulate neuronal survival and synaptic plasticity in the central nervous system (CNS) in an activity-dependent manner, but the underlying mechanisms remain unclear. Here we report that the number of BDNF receptor TrkB
Preconditioning selective ventral root injury promotes plasticity of ascending sensory neurons in the injured spinal cord of adult rats--possible roles of brain-derived neurotrophic factor, TrkB and p75 neurotrophin receptor.
Fang Li,Li Li,Xing-Yun Song,Jin-Hua Zhong,Xue-Gang Luo,Cory J Xian,Xin-Fu Zhou
The European Journal of Neuroscience null
S M Mooney et al.
Neuroscience, 149(2), 372-381 (2007-09-18)
Organotypic cultures of rat cortex were used to test the hypotheses that nerve growth factor (NGF) is neuroprotective for immature cortical neurons and that ethanol abolishes this neuroprotection in a developmental stage-dependent manner. Samples were obtained on gestational day (G)
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