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Key Documents

T-058

Supelco

Tapentadol hydrochloride solution

1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

Sinonimo/i:

Tapentadol hydrochloride solution

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About This Item

Formula empirica (notazione di Hill):
C14H23NO · HCl
Numero CAS:
Peso molecolare:
257.80
Numero CE:
Numero MDL:
Codice UNSPSC:
41116107
ID PubChem:
NACRES:
NA.24

Grado

certified reference material

Forma fisica

liquid

Caratteristiche

Snap-N-Spike®/Snap-N-Shoot®

Confezionamento

ampule of 1 mL

Produttore/marchio commerciale

Cerilliant®

drug control

Narcotic Licence Schedule A (Switzerland); estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal)

Concentrazione

1.0 mg/mL in methanol (as free base)

tecniche

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

applicazioni

forensics and toxicology

Formato

single component solution

Temperatura di conservazione

−20°C

Stringa SMILE

Cl.CC[C@H]([C@@H](C)CN(C)C)c1cccc(O)c1

InChI

1S/C14H23NO.ClH/c1-5-14(11(2)10-15(3)4)12-7-6-8-13(16)9-12;/h6-9,11,14,16H,5,10H2,1-4H3;1H/t11-,14+;/m0./s1
ZELFLGGRLLOERW-YECZQDJWSA-N

Informazioni sul gene

Descrizione generale

Tapentadol represents the first new drug of the centrally-acting analgesic class approved in the US in more than 25 years. This Snap-N-Spike® Reference Solution is suitable for many LC/MS or GC/MS applications, including forensic analysis, pharmaceutical analysis, pain prescription monitoring, and urine drug testing.

Applicazioni

  • Extended-Release Formulation for Chronic Pain: Extended-release formulations of Tapentadol hydrochloride are developed to provide sustained pain relief for chronic conditions. This formulation reduces the frequency of dosing and enhances patient compliance, offering consistent pain management (Faria et al., 2017).
  • Pharmaceutical Quality Control and Research: High-purity Tapentadol hydrochloride solutions are essential in pharmaceutical research and quality control. These solutions are used for the calibration of analytical instruments and ensuring the consistency and safety of pharmaceutical products (Fejos et al., 2014).
  • Transdermal Delivery Systems: Innovative research has developed PEGylated ultra-deformable transferosomes for the transdermal delivery of Tapentadol, improving its bioavailability and analgesic activity. This method offers a non-invasive alternative for pain management (Deng et al., 2022).
  • Innovative Pain Management Solutions: Research on new delivery methods, such as intranasal administration using chitosan nanoparticles, aims to enhance the therapeutic potential and patient compliance of Tapentadol hydrochloride solution for pain management (Javia & Thakkar, 2017).

Note legali

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Avvertenze

Danger

Indicazioni di pericolo

Classi di pericolo

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Organi bersaglio

Eyes,Central nervous system

Codice della classe di stoccaggio

3 - Flammable liquids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

49.5 °F - closed cup

Punto d’infiammabilità (°C)

9.7 °C - closed cup


Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Protocolli

To optimize hydrolysis using β-glucuronidase, factors such as incubation time, temperature, hydrolysis pH, enzyme source, and enzyme concentration must be evaluated for each glucuronide metabolite to be analyzed.

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