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H-076

Supelco

9-Hydroxyrisperidone solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Formula empirica (notazione di Hill):
C23H27FN4O3
Numero CAS:
144598-75-4
Peso molecolare:
426.48
Codice UNSPSC:
41116107
NACRES:
NA.24

Grado

certified reference material

Forma fisica

liquid

Caratteristiche

Snap-N-Spike®/Snap-N-Shoot®

Confezionamento

ampule of 1 mL

Produttore/marchio commerciale

Cerilliant®

Concentrazione

1.0 mg/mL in methanol

tecniche

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

applicazioni

clinical testing

Formato

single component solution

Condizioni di spedizione

wet ice

Temperatura di conservazione

−20°C

Stringa SMILE

CC1=C(CCN2CCC(CC2)c3noc4cc(F)ccc34)C(=O)N5CCCC(O)C5=N1

InChI

1S/C23H27FN4O3/c1-14-17(23(30)28-9-2-3-19(29)22(28)25-14)8-12-27-10-6-15(7-11-27)21-18-5-4-16(24)13-20(18)31-26-21/h4-5,13,15,19,29H,2-3,6-12H2,1H3
PMXMIIMHBWHSKN-UHFFFAOYSA-N

Informazioni sul gene

human ... DRD2(1813) , HTR2A(3356)

Categorie correlate

Descrizione generale

A Snap-N-Spike® Reference Solution suitable to use in LC/MS or GC/MS applications for urine drug testing, clinical toxicology, and forensic analysis. Also known as paliperidone, 9-Hydroxyrisperidone is sold under the brand name Invega, an atypical antipsychotic used for acute and maintenance treatment of schizophrenia. The drug is also the primary metabolite of risperidone, marketed as the atypical antipsychotic Risperdal®.

Applicazioni


  • 9-HydroxyrisperiDonesolution for in vitro research: Employed in pharmacological studies to investigate dual antipsychotic therapies in treatment-resistant conditions, enhancing the understanding of drug interactions and efficacy (Warnick et al., 2024).

  • High-purity 9-HydroxyrisperiDoneliquid for pharmacological studies: Utilized in crystallography research to assess the impact of alkyl chain length on the crystallization behavior of related compounds, providing insights into drug formulation strategies (Chen et al., 2024).

  • Buy 9-HydroxyrisperiDonesolution for receptor binding assays: Applied in the development of novel drug delivery systems such as dissolving microneedles, enhancing the administration of long-acting antipsychotic treatments (Londhe and Bhadale, 2023).

  • 9-HydroxyrisperiDoneactive metabolite for antipsychotic research: Analyzed in postmortem toxicological assessments to identify metabolites, improving forensic analysis techniques and therapeutic drug monitoring (Yamagishi et al., 2023).

  • Analytical standard 9-HydroxyrisperiDonefor biochemistry labs: Investigated in the synthesis of prodrug microcrystals for extended-release formulations, aiding in the design of more effective and patient-friendly antipsychotic medications (Xu et al., 2022).




Note legali

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Risperdal is a registered trademark of Johnson & Johnson
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Avvertenze

Danger

Indicazioni di pericolo

H225,H301 + H311 + H331,H370

Classi di pericolo

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Organi bersaglio

Eyes

Codice della classe di stoccaggio

3 - Flammable liquids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

49.5 °F - closed cup

Punto d’infiammabilità (°C)

9.7 °C - closed cup

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Risperidone United States Pharmacopeia (USP) Reference Standard

USP

1604654

Risperidone

Drug and therapeutics bulletin, 50(9), 102-105 (2012-09-12)
For over 40 years, antipsychotic drugs have been used as long-term maintenance treatment to control symptoms and reduce relapse rates in patients with schizophrenia. 'First-generation' oral agents such as haloperidol and chlorpromazine are associated with high levels of unwanted neurological
Caroline M Perry
Paediatric drugs, 14(6), 417-427 (2012-10-12)
Paliperidone, the major active metabolite of risperidone, is an atypical antipsychotic agent formulated as an extended-release (ER) tablet suitable for once-daily oral administration. Paliperidone ER is approved for the treatment of adolescents aged 12-17 years with schizophrenia in the US
Pierre S Chue et al.
Expert review of neurotherapeutics, 12(12), 1399-1410 (2012-12-15)
Paliperidone, or 9-hydroxyrisperidone (Invega(®), Janssen, Antwerp, Belgium) is the major active metabolite of the atypical antipsychotic risperidone (Risperdal(®), Janssen). It possesses a similar, though not identical, receptor pharmacology to the parent molecule. There are additional differences in terms of its
Yvette Roke et al.
Journal of child and adolescent psychopharmacology, 22(6), 432-439 (2012-12-14)
The aim of this study was to investigate the long-term treatment effects of risperidone on prolactin levels and prolactin-related side effects in pubertal boys with autism spectrum disorders (ASD) and disruptive behavior disorders (DBD). Physical healthy 10-20-year-old males with ASD
Treating residual insomnia in schizophrenia: examining the options.
C Andrade et al.
Acta psychiatrica Scandinavica, 127(1), 11-11 (2012-12-18)
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