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Documenti fondamentali

870336C

Avanti

Soy PS

Avanti Research - A Croda Brand 870336C

Sinonimo/i:

L-α-phosphatidylserine (Soy, 99%) (sodium salt)

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About This Item

Numero CAS:
Codice UNSPSC:
12352211
NACRES:
NA.25

Stato

liquid

Confezionamento

pkg of 1 × 2.5 mL (870336C-25mg)
pkg of 2 × 4 mL (870336C-200mg)
pkg of 5 × 4 mL (870336C-500mg)

Produttore/marchio commerciale

Avanti Research - A Croda Brand 870336C

Concentrazione

10 mg/mL (870336C-25mg)
25 mg/mL (870336C-200mg)
25 mg/mL (870336C-500mg)

Tipo di lipide

phosphoglycerides

Condizioni di spedizione

dry ice

Temperatura di conservazione

−20°C

Stringa SMILE

[H][C@@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)(OC(CCCCCCC/C=C\C/C=C\CCCCC)=O)COC(CCCCCCCCCCCCCCC)=O.[Na+]

InChI

1S/C40H74NO10P.Na/c1-3-5-7-9-11-13-15-17-18-20-22-24-26-28-30-32-39(43)51-36(34-49-52(46,47)50-35-37(41)40(44)45)33-48-38(42)31-29-27-25-23-21-19-16-14-12-10-8-6-4-2;/h11,13,17-18,36-37H,3-10,12,14-16,19-35,41H2,1-2H3,(H,44,45)(H,46,47);/q;+1/p-1/b13-11-,18-17-;/t36-,37+;/m1./s1
WPLLCKLCLMRAPV-WHVRKWPVSA-M

Descrizione generale

Phosphatidylserine (PS) is one of the major phospholipids in biological tissues and food samples. PS has unsaturated acyl chains in their structure.

Applicazioni

Soy PS is suitable for use:
  • as standard and in the preparation of calibration curve for liquid chromatography-tandem mass spectrometry (LC-MS/MS)
  • in the preparation of lipid bilayer disks
  • as a substrate to determine the interaction of anionic lipids with Clostridium sordellii lethal toxin-N terminal catalytic domain (TcsL-cat)
  • in the preparation of liposomes mimicking the inner mitochondrial membrane

Azioni biochim/fisiol

Phosphatidylserine (PS) is mainly present in the cytosolic leaflet of plasma membrane, endosomes and lysosomes. It is also present in the interior of the endoplasmic reticulum, Golgi complex and mitochondria. PS is the preferential binding substrate for Clostridium sordellii lethal toxin (TcsL). PS is a component of the lipid-calcium-phosphate complex for deposition during bone formation, regulation of apoptosis and blood coagulation.

Confezionamento

5 mL Clear Glass Sealed Ampule (870336C-200mg)
5 mL Clear Glass Sealed Ampule (870336C-25mg)
5 mL Clear Glass Sealed Ampule (870336C-500mg)

Note legali

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pittogrammi

Skull and crossbonesHealth hazard

Avvertenze

Danger

Classi di pericolo

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

Organi bersaglio

Liver,Kidney, Respiratory system

Codice della classe di stoccaggio

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

does not flash

Punto d’infiammabilità (°C)

does not flash


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Certificati d'analisi (COA)

Lot/Batch Number

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Validation of an LC-MS/MS method for the quantification of choline-related compounds and phospholipids in foods and tissues
Xiong Y, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 911, 170-179 (2012)
Evaluation of bilayer disks as plant cell membrane models in partition studies
Boija E, et al.
Analytical biochemistry, 364(2), 145-152 (2007)
Effect of ubiquinone-10 on the stability of biomimetic membranes of relevance for the inner mitochondrial membrane
Eriksson EK, et al.
Biochimica et Biophysica Acta - Biomembranes, 1860(5), 1205-1215 (2018)
The use of natural and synthetic phospholipids as pharmaceutical excipients
van Hoogevest P and Wendel A
European Journal of Lipid Science and Technology, 116(9), 1088-1107 (2014)
The catalytic domains of Clostridium sordellii lethal toxin and related large clostridial glucosylating toxins specifically recognize the negatively charged phospholipids phosphatidylserine and phosphatidic acid
Varela Chavez C, et al.
Cellular Microbiology, 17(10), 1477-1493 (2015)

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