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850445C

Avanti

14:0-16:0 PC

1-myristoyl-2-palmitoyl-sn-glycero-3-phosphocholine, chloroform

Sinonimo/i:

1-tetradecanoyl-2-hexadecanoyl-sn-glycero-3-phosphocholine; MPPC; PC(14:0/16:0)

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About This Item

Formula empirica (notazione di Hill):
C38H76NO8P
Numero CAS:
69525-80-0
Peso molecolare:
705.99
Codice UNSPSC:
51191904
NACRES:
NA.25

Saggio

>99% (TLC)

Forma fisica

liquid

Confezionamento

pkg of 1 × 2.5 mL (850445C-25mg)
pkg of 1 × 20 mL (850445C-500mg)

Produttore/marchio commerciale

Avanti Research™ - A Croda Brand 850445C

Concentrazione

10 mg/mL (850445C-25mg)
25 mg/mL (850445C-500mg)

Tipo di lipide

cardiolipins
phospholipids

Condizioni di spedizione

dry ice

Temperatura di conservazione

−20°C

InChI

1S/C38H76NO8P/c1-6-8-10-12-14-16-18-19-21-23-25-27-29-31-38(41)47-36(35-46-48(42,43)45-33-32-39(3,4)5)34-44-37(40)30-28-26-24-22-20-17-15-13-11-9-7-2/h36H,6-35H2,1-5H3/t36-/m1/s1
RFVFQQWKPSOBED-PSXMRANNSA-N

Descrizione generale

Phosphatidylcholine (PC) is dietary source of choline. 14:0-16:0 PC (1-myristoyl-2-palmitoyl-sn-glycero-3-phosphocholine) is a water-soluble lysolipid. 14:0-16:0 PC is a symmetrical phosphatidylcholine.

Applicazioni

14:0-16:0 PC (1-myristoyl-2-palmitoyl-sn-glycero-3-phosphocholine) has been used to generate Wnt3a liposomes. It has also been used as a calibration standard for lipidomic analysis by liquid chromatography–tandem mass spectrometry (LC-MS). It may be used in the bilayer membrane to study its miscibility with d-erythro-N-palmitoyl-sphingomyelin (16:0-SM) using differential scanning calorimetry (DSC).

Azioni biochim/fisiol

Phosphatidylcholine (PC) is involved in the fusion and transport of membranes. It is known to play a vital role in endocytosis and the catalytic activity of enzymes.

Confezionamento

30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (850445C-500mg)
5 mL Clear Glass Sealed Ampule (850445C-25mg)

Note legali

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pittogrammi

Skull and crossbonesHealth hazard
GHS06,GHS08

Avvertenze

Danger

Classi di pericolo

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

Organi bersaglio

Liver,Kidney, Respiratory system

Codice della classe di stoccaggio

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

does not flash

Punto d’infiammabilità (°C)

does not flash

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Jeffrey K Mills et al.
Biochimica et biophysica acta, 1716(2), 77-96 (2005-10-12)
The enhanced permeability of lipid bilayer membranes at their gel-to-liquid phase transition has been explained using a "bilayer lipid heterogeneity" model, postulating leaky interfacial regions between still solid and melting liquid phases. The addition of lysolipid to dipalmitoylphosphatidylcholine bilayers dramatically
Bohdana Térová et al.
Biochimica et biophysica acta, 1667(2), 182-189 (2004-12-08)
In this study we have used differential scanning calorimetry (DSC) to study the miscibility of different saturated phosphatidylcholines (PCs) with D-erythro-N-palmitoyl-sphingomyelin (16:0-SM). Information about the miscibility was obtained by observing the thermotropic phase behavior of binary mixtures of saturated PCs
Li-Juan Zhao et al.
Journal of ethnopharmacology, 260, 112943-112943 (2020-05-19)
Arenobufagin (ArBu) is an important anti-tumor ingredient of Chan'su which has long been used as traditional Chinese medicine in clinic for tumor therapy in China. The purpose of our study is to investigate the lipid homeostasis regulation effects of ArBu
Nathan T Morrell et al.
PloS one, 3(8), e2930-e2930 (2008-08-14)
Wnt signals exercise strong cell-biological and regenerative effects of considerable therapeutic value. There are, however, no specific Wnt agonists and no method for in vivo delivery of purified Wnt proteins. Wnts contain lipid adducts that are required for activity and
Dana K Shaw et al.
Nature communications, 8, 14401-14401 (2017-02-15)
The insect immune deficiency (IMD) pathway resembles the tumour necrosis factor receptor network in mammals and senses diaminopimelic-type peptidoglycans present in Gram-negative bacteria. Whether unidentified chemical moieties activate the IMD signalling cascade remains unknown. Here, we show that infection-derived lipids

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