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750332C

Avanti

14:0 Cardiolipin (sodium salt)

1′,3′-bis[1,2-dimyristoyl-sn-glycero-3-phospho]-glycerol (sodium salt), chloroform

Sinonimo/i:

1,1′,2,2′-tetratetradecanoyl cardiolipin (sodium salt); CL(1′-[14:0/14:0],3′-[14:0/14:0])

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About This Item

Formula empirica (notazione di Hill):
C65H124Na2O17P2
Numero CAS:
63988-21-6
Peso molecolare:
1285.60
Numero MDL:
MFCD00201315
Codice UNSPSC:
51191904
NACRES:
NA.25

Saggio

>99% (TLC)

Stato

solution

Confezionamento

pkg of 1 × 2.5 mL (750332C-25mg)
pkg of 2 × 4 mL (750332C-200mg)

Produttore/marchio commerciale

Avanti Research™ - A Croda Brand 750332C

Concentrazione

10 mg/mL (750332C-25mg)
25 mg/mL (750332C-200mg)

Tipo di lipide

phospholipids
cardiolipins

Condizioni di spedizione

dry ice

Temperatura di conservazione

−20°C

Descrizione generale

Cardiolipin, the mitochondrial-specific phospholipid, helps maintain mitochondrial function, membrane potential and structural support for the inner mitochondrial membrane and the proteins in it. Concentration and composition changes of cardiolipin have been implicated in pathological conditions including ischemia, hypothyroidism, aging, heart failure and cardioskeletal myopathy (Barth syndrome). Cardiolipin has also been shown as a signaling molecule in apoptosis.

Applicazioni

14:0 Cardiolipin (sodium salt) has been used for the mass spectrometry (MS) analysis to determine the structure of lipid A.

Confezionamento

5 mL Clear Glass Sealed Ampule (750332C-200mg)
5 mL Clear Glass Sealed Ampule (750332C-25mg)

Note legali

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pittogrammi

Skull and crossbonesHealth hazard
GHS06,GHS08

Avvertenze

Danger

Classi di pericolo

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Organi bersaglio

Central nervous system, Liver,Kidney

Classe di pericolosità dell'acqua (WGK)

WGK 3

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Certificati d'analisi (COA)

Lot/Batch Number

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Avanti

840012C

Heart CA

Cardiolipina 4.7-5.3 mg/mL in ethanol, ≥97% (TLC)

Sigma-Aldrich

C1649

Cardiolipina

18:1 Cardiolipin Avanti Research™ - A Croda Brand

Avanti

710335P

18:1 Cardiolipin

Rapid lipid a structure determination via surface acoustic wave nebulization and hierarchical tandem mass spectrometry algorithm
Yoon SH, et al.
Rapid Communications in Mass Spectrometry, 30(23), 2555-2560 (2016)
Vladimir B Ritov et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 831(1-2), 63-71 (2005-12-13)
Cardiolipin is a phospholipid that is specific to the inner mitochondrial membrane and essential for numerous mitochondrial functions. Accordingly, a quantitative assay for cardiolipin can be a valuable aspect of assessing mitochondrial content and functional capacity. The current study was
Role of cardiolipin alterations in mitochondrial dysfunction and disease
Chicco AJ and Sparagna GC
American Journal of Physiology. Cell Physiology, 292(1), C33-C44 (2007)
Erum Malik et al.
Biochimica et biophysica acta. Biomembranes, 1862(2), 183141-183141 (2019-12-04)
Linearized esculentin 2 EM (E2EM-lin) from the frog, Glandirana emeljanovi was highly active against Gram-positive bacteria (minimum lethal concentration ≤ 5.0 μM) and strongly α-helical in the presence of lipid mimics of their membranes (>55.0%). The N-terminal α-helical structure adopted by E2EM-lin showed
Na Li et al.
Analytical chemistry, 91(24), 15873-15882 (2019-11-14)
The matrix plays a prominent role in expanding the ability of matrix assisted laser desorption/ionization mass spectrometry (MALDI MS). However, on account of the unclarity of necessary properties of the matrix in MALDI MS, development of a new matrix is
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