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Documenti fondamentali

700122P

Avanti

campestanol

Avanti Research™ - A Croda Brand 700122P, powder

Sinonimo/i:

5α-campestan-3β-ol

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About This Item

Formula empirica (notazione di Hill):
C28H50O
Numero CAS:
474-60-2
Peso molecolare:
402.70
Numero MDL:
MFCD00201592
Codice UNSPSC:
12352211
NACRES:
NA.25

Saggio

>99% (TLC)

Stato

powder

Confezionamento

pkg of 1 × 1 mg (700122P-1mg)

Produttore/marchio commerciale

Avanti Research™ - A Croda Brand 700122P

Condizioni di spedizione

dry ice

Temperatura di conservazione

−20°C

Stringa SMILE

O[C@@H]1C[C@H]2[C@@]([C@@H]3[C@H]([C@H]4[C@@]([C@H](CC4)[C@@H](CC[C@H](C(C)C)C)C)(CC3)C)CC2)(CC1)C

InChI

1S/C28H50O/c1-18(2)19(3)7-8-20(4)24-11-12-25-23-10-9-21-17-22(29)13-15-27(21,5)26(23)14-16-28(24,25)6/h18-26,29H,7-17H2,1-6H3/t19-,20-,21+,22+,23+,24-,25+,26+,27+,28-/m1/s1
ARYTXMNEANMLMU-ATEDBJNTSA-N

Descrizione generale

Campestanol has a methyl group at the C-24. It comprises the 10-30% of stanol content in vegetable oil. It is naturally occurring and has similar structure as cholesterol. Campestanol is synthesized by the hydrogenation of campesterol.
Campestanol is a saturated plant stanol.

Azioni biochim/fisiol

Campestanol absorption in intestine is similar to that of cholesterol absorption pathway. However, in sitosterolemic homozygotes, it is hyperabsorbed from the intestine.
Intestinal absorption of campestanol is lesser compared to cholesterol due to the presence of side chain. Due to the structural similarity with cholesterol, campestanol reduces cholesterol absorption in the intestine and the plasma level of LDL cholesterol.

Confezionamento

5 mL Amber Glass Screw Cap Vial (700122P-1mg)

Note legali

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Codice della classe di stoccaggio

11 - Combustible Solids

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Certificati d'analisi (COA)

Lot/Batch Number

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Cycloartenol ≥90% (GC)

Sigma-Aldrich

08172

Cycloartenol

5α-Cholestan-3β-ol ≥95%

Sigma-Aldrich

D6128

5α-Cholestan-3β-ol

β-Sitosterol from soybean, ≥96%

Sigma-Aldrich

S9889

β-Sitosterol

β-Sitosterol synthetic, ≥95%

Sigma-Aldrich

S1270

β-Sitosterol

Brassinosteroid deficiency due to truncated steroid 5alpha-reductase causes dwarfism in the lk mutant of pea
Nomura , et al.
Plant Physiology, 135(4), 2220-2229 (2004)
SOFW Journal, 149-149 (2002)
Campestanol (24-methyl-5alpha-cholestan-3beta-ol) absorption and distribution in New Zealand white rabbits: effect of dietary sitostanol
Xu G, et al.
Metabolism, Clinical and Experimental, 48(3), 363-368 (1999)
Hyperabsorption and retention of campestanol in a sitosterolemic homozygote: comparison with her mother and three control subjects
Salen, Gerald and Xu, Guorong and Tint, GS and Batta, AK and Shefer, Sarah
Journal of Lipid Research, 41(11), 1883-1889 (2000)
Campestanol (24-methyl-5alpha-cholestan-beta-ol) absorption and distribution in New Zealand white rabbits: effect of dietary sitostanol
Xu G, et al.
Metabolism and Disease, 48(3), 363-368 (1999)
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