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Key Documents

W431300

Sigma-Aldrich

Hesperetin

≥95%

Sinonimo/i:

3′,5,7-Trihydroxy-4′-methoxyflavanone, 5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-chromanone

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About This Item

Formula empirica (notazione di Hill):
C16H14O6
Numero CAS:
Peso molecolare:
302.28
Numero FEMA:
4313
Numero MDL:
Codice UNSPSC:
12164502
ID PubChem:
Numero Flavis:
16.097
NACRES:
NA.21

Origine biologica

synthetic

Saggio

≥95%

Forma fisica

powder (with a light tan cast)

Punto di fusione

227-232 °C

applicazioni

flavors and fragrances

Documentazione

see Safety & Documentation for available documents

Allergene alimentare

no known allergens

Organolettico

odorless

Stringa SMILE

COc1ccc(cc1O)C2CC(=O)c3c(O)cc(O)cc3O2

InChI

1S/C16H14O6/c1-21-13-3-2-8(4-10(13)18)14-7-12(20)16-11(19)5-9(17)6-15(16)22-14/h2-6,14,17-19H,7H2,1H3
AIONOLUJZLIMTK-UHFFFAOYSA-N

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Esclusione di responsabilità

For R&D or non-EU Food use. Not for retail sale.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


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Certificati d'analisi (COA)

Lot/Batch Number

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Hesperidin Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1794

Hesperidin

Eriodictyol ≥95.0% (HPLC)

Sigma-Aldrich

94258

Eriodictyol

Tangeretin ≥95% (HPLC)

Sigma-Aldrich

T8951

Tangeretin

Narirutin phyproof® Reference Substance

PHL83339

Narirutin

Naringin ≥90% (HPLC), from citrus fruit

Sigma-Aldrich

N1376

Naringin

Naringin ≥95% (HPLC)

Sigma-Aldrich

71162

Naringin

Sinensetin ≥98% (HPLC)

Sigma-Aldrich

SML1787

Sinensetin

Apigenin ≥97% (TLC), from citrus

Sigma-Aldrich

SMB00702

Apigenin

Elena Valeria Fuior et al.
Pharmaceutics, 11(8) (2019-08-07)
Citrus flavonoids have well-documented protective effects on cardiovascular system, but the poor water solubility and reduced bioavailability restrict their therapeutic use. We aimed to overcome these limitations and encapsulated naringenin and hesperetin into lipid nanoemulsions (LNs), targeted to vascular cell
Ramesh Elango et al.
Journal of Asian natural products research, 20(6), 559-569 (2017-05-26)
We studied the chemoprevention property of hesperetin on H522 cells using MTT, an apoptosis assay, an analysis of cell cycle progression, and the mitochondrial membrane potential, and apoptotic marker gene expression was determined using quantitative PCR. Hesperetin enhanced apoptotic cell
Weixin Wang et al.
Journal of agricultural and food chemistry, 63(43), 9488-9495 (2015-10-13)
The objective of this study was to investigate the ability of resveratrol and hesperetin to scavenge acrolein at pH 7.4 and 37 °C. About 6.4 or 5.2% of acrolein remained after reaction with resveratrol or hesperetin for 12 h at
Jose Valdo Madeira et al.
Biotechnology progress, 31(5), 1273-1279 (2015-06-18)
Recent studies have pointed to a reduction in the incidence of some cancers, diabetes, and neuro-degenerative diseases as a result of human health benefits from flavanones. Currently, flavanones are obtained by chemical synthesis or extraction from plants, and these processes
Manuel Y Schär et al.
The American journal of clinical nutrition, 101(5), 931-938 (2015-03-20)
Epidemiologic data suggest inverse associations between citrus flavanone intake and cardiovascular disease (CVD) risk. However, insufficient randomized controlled trial data limit our understanding of the mechanisms by which flavanones and their metabolites potentially reduce cardiovascular risk factors. We examined the

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