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W421501

Sigma-Aldrich

Tyramine

98%, FG

Sinonimo/i:

2-(4-Hydroxyphenyl)ethylamine, 4-(2-Aminoethyl)phenol, 4-Hydroxyphenethylamine

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About This Item

Formula condensata:
HOC6H4CH2CH2NH2
Numero CAS:
51-67-2
Peso molecolare:
137.18
Numero FEMA:
4215
Beilstein:
1099914
Numero CE:
200-115-8
Numero MDL:
MFCD00008193
Codice UNSPSC:
12164502
ID PubChem:
329830683
Numero Flavis:
11.007
NACRES:
NA.21

Origine biologica

synthetic

Grado

FG

Conformità normativa

EU Regulation 1334/2008 & 872/2012
FDA 21 CFR 110

Saggio

98%

P. ebollizione

175-181 °C/8 mmHg (lit.)

Punto di fusione

160-162 °C (lit.)

applicazioni

flavors and fragrances

Documentazione

see Safety & Documentation for available documents

Allergene alimentare

no known allergens

Organolettico

meaty; phenolic

Stringa SMILE

NCCc1ccc(O)cc1

InChI

1S/C8H11NO/c9-6-5-7-1-3-8(10)4-2-7/h1-4,10H,5-6,9H2
DZGWFCGJZKJUFP-UHFFFAOYSA-N

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Categorie correlate

Azioni biochim/fisiol

Can enter catecholaminergic terminals and be released as a false transmitter.

Pittogrammi

Exclamation mark
GHS07

Avvertenze

Warning

Indicazioni di pericolo

H315,H319,H335

Classi di pericolo

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organi bersaglio

Respiratory system

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves

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Certificati d'analisi (COA)

Lot/Batch Number
SHBN7388
SHBN5574
SHBM2788
SHBL7434
MKCH7524

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Biotinyl tyramide ≥97% (HPLC)

Sigma-Aldrich

SML2135

Biotinyl tyramide

Dopamine hydrochloride

Sigma-Aldrich

H8502

Dopamine hydrochloride

N-Hydroxysuccinimide 98%

Sigma-Aldrich

130672

N-Hydroxysuccinimide

Giris Jacob et al.
Circulation, 107(19), 2475-2479 (2003-04-23)
Despite the widespread use of tyramine as a pharmacological tool to assess the effects of norepinephrine release from sympathetic nerve terminals, its vascular effects are not adequately characterized. In particular, previous results indicate that intravenous tyramine produces little if any
Tony Huynh et al.
The Journal of pathology, 231(2), 223-235 (2013-06-25)
The over-expression of NF-κB signalling in both muscle and immune cells contribute to the pathology in dystrophic muscle. The anti-inflammatory properties of glucocorticoids, mediated predominantly through monomeric glucocorticoid receptor inhibition of transcription factors such as NF-κB (transrepression), are postulated to
Stephan A Chalon et al.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 28(9), 1685-1693 (2003-06-05)
Evidence suggests that compounds that increase the synaptic availability of more than one neurotransmitter have greater efficacy in the treatment of depression than single-acting drugs. Preclinical studies indicate that duloxetine acts to inhibit serotonin (5-HT) and norepinephrine (NE) transporters. The
D R Varma et al.
The Journal of pharmacology and experimental therapeutics, 265(3), 1096-1104 (1993-06-01)
At concentrations higher than that required to produce maximal vasoconstriction, tyramine caused concentration-dependent relaxation of rat aortic strips contracted maximally by tyramine, norepinephrine, phenylephrine, 5-hydroxytryptamine, prostaglandin F2 alpha, endothelin, angiotensin II and potassium; isoproterenol did not relax potassium-contracted strips. The
Adam B Braunschweig et al.
Nano letters, 7(7), 2030-2036 (2007-06-15)
Tyrosinase activity is monitored by pi-donor-acceptor force interactions between a bipyridinium-modified AFM tip and the biocatalytic reaction product generated on a tyramine- (or dopamine-) modified surface. Upon oxidation of the surface to dopaquinone as a result of tyrosinase activity, force
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