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Merck
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Key Documents

Altri documenti

H49804

Sigma-Aldrich

2-Hydroxyphenylacetic acid

ReagentPlus®, 99%

Sinonimo/i:

(2-Hydroxyphenyl)acetic acid, (o-Hydroxyphenyl)acetic acid, 2-(2-Hydroxyphenyl)acetic acid, 2-(2′-Hydroxyphenyl)acetic acid, 2-HPAA, 2-Hydroxybenzeneacetic acid

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About This Item

Formula condensata:
HOC6H4CH2CO2H
Numero CAS:
614-75-5
Peso molecolare:
152.15
Beilstein:
908000
Numero CE:
210-393-2
Numero MDL:
MFCD00004323
Codice UNSPSC:
12352100
ID PubChem:
24895662
NACRES:
NA.22

Livello qualitativo

100

Nome Commerciale

ReagentPlus®

Saggio

99%

Punto di fusione

145-147 °C (lit.)

Stringa SMILE

OC(=O)Cc1ccccc1O

InChI

1S/C8H8O3/c9-7-4-2-1-3-6(7)5-8(10)11/h1-4,9H,5H2,(H,10,11)
CCVYRRGZDBSHFU-UHFFFAOYSA-N

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Categorie correlate

Note legali

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Pittogrammi

Exclamation mark
GHS07

Avvertenze

Warning

Indicazioni di pericolo

H315 - H319 - H335

Classi di pericolo

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organi bersaglio

Respiratory system

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves

Certificati d'analisi (COA)

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Tania Irebo et al.
Journal of the American Chemical Society, 130(29), 9194-9195 (2008-06-28)
Proton coupled electron transfer (PCET) from tyrosine covalently linked to Ru(bpy)32+ has been studied with laser flash-quench techniques. Two new complexes with internal hydrogen bonding bases to the phenolic proton have been synthesized. Depending on the hydrogen bonding and protonation
D Ratanasavanh et al.
Fundamental & clinical pharmacology, 10(6), 504-510 (1996-01-01)
We compared the cytotoxic effect of coumarin and its derivatives, 7-hydroxycoumarin (7-OHC), 4-hydroxycoumarin (4-OHC), o-hydroxyphenyl acetic acid (OHPAA) and o-coumaric acid (CA), on cultured hepatocytes from human, rat, mouse and rabbit liver. At 10(-5) and 5 x 10(-5) M, coumarin
M Bayat-Sarmadi et al.
Molecular and cellular endocrinology, 92(1), 127-134 (1993-03-01)
Prolactin has many known functions and one of them is to induce the expression of milk protein gene expression in the mammary gland. Specific membrane receptors have been recently characterized but the transduction mechanism involved in the transfer of the
S L Born et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 41(2), 247-258 (2002-12-14)
Coumarin, a well recognized rat hepatotoxicant, also causes acute, selective necrosis of terminal bronchiolar Clara cells in the mouse lung. Further, chronic oral gavage administration of coumarin at 200 mg/kg, a dose that causes Clara cell death, resulted in a
Jeffrey D Vassallo et al.
Toxicological sciences : an official journal of the Society of Toxicology, 80(2), 249-257 (2004-05-14)
Hepatotoxicity of coumarin is attributed to metabolic activation to an epoxide intermediate, coumarin 3,4-epoxide (CE). However, whereas rats are most susceptible to coumarin-induced hepatotoxicity, formation of CE is greatest in mouse liver microsomes, a species showing little evidence of hepatotoxicity.
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