94295
3-Ureidopropionic acid
≥98.0% (T)
Sinonimo/i:
N-Carbamoyl-β-alanine
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About This Item
Formula condensata:
NH2CONHCH2CH2COOH
Numero CAS:
Peso molecolare:
132.12
Beilstein:
1705263
Numero MDL:
Codice UNSPSC:
12352106
ID PubChem:
NACRES:
NA.22
Prodotti consigliati
Livello qualitativo
Saggio
≥98.0% (T)
Forma fisica
powder
Impiego in reazioni chimiche
reaction type: solution phase peptide synthesis
Punto di fusione
170-175 °C (dec.)
applicazioni
peptide synthesis
Stringa SMILE
NC(=O)NCCC(O)=O
InChI
1S/C4H8N2O3/c5-4(9)6-2-1-3(7)8/h1-2H2,(H,7,8)(H3,5,6,9)
JSJWCHRYRHKBBW-UHFFFAOYSA-N
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Categorie correlate
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
Dispositivi di protezione individuale
Eyeshields, Gloves, type N95 (US)
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M M Matthews et al.
The Journal of biological chemistry, 262(15), 7232-7237 (1987-05-25)
N-Carbamoyl-beta-alanine (NC beta A) amidohydrolase (EC 3.5.1.6) is regulated in opposing fashion by the substrate, NC beta A and the product, beta-alanine. The native enzyme from rat liver has a molecular weight of 235,000 in the absence of ligands. NC
S Kölker et al.
Journal of neuroscience research, 66(4), 666-673 (2001-12-18)
3-Ureidopropionate (3-UPA) is a physiologic metabolite in pyrimidine degradation. Pathological accumulation of 3-UPA in body fluids is found in 3-ureidopropionase deficiency and severe forms of propionic aciduria. Both diseases clinically present with a severe neuropathology involving gray and white matter
C Engelbrecht et al.
The International journal of biochemistry, 17(4), 495-501 (1985-01-01)
The metabolism of [5-3H]uridine and the incorporation of the precursor into liver RNA was studied in developing (13-day-old) and adult (45-day-old) mice. Different time-courses of labelling and increased amounts of labelled catabolic products of uridine were found in liver and
A B Van Kuilenburg et al.
Analytical biochemistry, 272(2), 250-253 (1999-07-23)
A radiochemical assay was developed to measure the activity of beta-ureidopropionase in human liver homogenates which is based on the detection of the reaction product (14)CO(2) by liquid scintillation counting. Radiolabeled N-carbamyl-beta-alanine was prepared within 15 min by a simple
J Yaplito-Lee et al.
Molecular genetics and metabolism, 93(2), 190-194 (2007-10-30)
Beta-ureidopropionase deficiency (McKusick 606673) is an autosomal recessive condition caused by mutations in the UPB1 gene. To date, five patients have been reported, including one putative case detected through newborn screening. Clinical presentation includes neurological and developmental problems. Here, we
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