912034
Trimethyl chitosan
high molecular weight, degree of quaternization 30-70%
Sinonimo/i:
N,N,N-Trimethyl chitosan, Chitosan trimethyl, Mucoadhesive polymers, TMC Chitosan
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About This Item
Prodotti consigliati
Livello qualitativo
Forma fisica
powder
Colore
light yellow to light brown
Temperatura di conservazione
2-8°C
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Applicazioni
Chitosan offers remarkable biological properties, it has been widely used in drug delivery and tissue engineering applications. Chitosan has good mucoadhesive properties due to its positive charge, which increases the adhesion to mucosa and facilitates drug penetration. Also, chitosan possesses hemostatic properties, which makes it a good candidate for wound dressing applications.
The quaternization of the primary amine increases the water solubility of chitosan and keeps chitosan soluble over a wide pH range. Among all the quaternized chitosans, N, N, N-trimethyl chitosan chloride (TMC) is the most widely applied in biomedical applications.
The quaternization of the primary amine increases the water solubility of chitosan and keeps chitosan soluble over a wide pH range. Among all the quaternized chitosans, N, N, N-trimethyl chitosan chloride (TMC) is the most widely applied in biomedical applications.
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
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Journal of Metals, Materials and Minerals, 18(2), 59-65 (2008)
Biomaterials, 27(31), 5377-5390 (2006-07-21)
A novel class of hyperbranched polymers based on polyglycerol (PG) and poly(ethylene glycol) (PEG) are synthesized by multibranching anionic ring opening polymerization. Multivalent cationic sites are added to these polymers by a post-amination and quarternization reactions. Blood compatibility studies using
Preparation and NMR characterization of highly substituted IV-trimethyl chitosan chloride.
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Biomacromolecules, 9(3), 886-895 (2008-02-06)
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