909858
Carboxylic acid-poly(ethylene glycol)-b-poly(lactide-co-glycolide)
PEG average Mn 5,000, PLGA average Mn 20,000, lactide:glycolide 50:50
Sinonimo/i:
COOH-PEG-PLGA, Carboxylic acid PEG-PLGA
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About This Item
Formula condensata:
H[(C3H4O2)x(C2H2O2)y]mO[C2H4O]nC2H3O2
Codice UNSPSC:
12352106
NACRES:
NA.23
Prodotti consigliati
Forma fisica
powder or chunks
Rapporto d’alimentazione
lactide:glycolide 50:50
PM
PEG average Mn 5,000 (by NMR)
PLGA average Mn 20,000 (by NMR)
Colore
white to tan
Temperatura di conservazione
−20°C
Applicazioni
Carboxylic acid-poly(ethylene glycol)-b-poly(lactide-co-glycolide) is a functionalized, amphiphilic, diblock copolymer composed of a hydrophilic PEG block and a hydrophobic PLGA block. These biodegradable, biocompatible polymers can self-assemble to form nanoparticles, such as micelles and polymersomes, in both aqueous and non-aqueous media. Due to these properties, these polymers are widely used in polymeric nanoparticle formulation to achieve controlled and targeted delivery of therapeutic agents (e.g. APIs, genetic material, peptides, vaccines, and antibiotics). The carboxylic acid functional group on the PEG chain enables rapid and facile surface functionalization, allowing for these materials to be used in applications such as targeted drug delivery.
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
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