909769
Folate-poly(ethylene glycol)-b-poly(lactide-co-glycolide)
PEG average Mn 2,000, PLGA average Mn 10,000, lactide:glycolide 50:50
Sinonimo/i:
Biotin-PEG-PLGA, Polyethylene glycol
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About This Item
Formula condensata:
H[(C3H4O2)x(C2H2O2)y]mO[C2H4O]nC25H29N11O8
Codice UNSPSC:
51171641
NACRES:
NA.23
Prodotti consigliati
Forma fisica
powder or chunks
Rapporto d’alimentazione
lactide:glycolide 50:50
PM
PEG average Mn 2,000 (by NMR)
PLGA average Mn 10,000 (by NMR)
Colore
white to tan
Temperatura di conservazione
−20°C
Categorie correlate
Applicazioni
Folate-poly(ethylene glycol)-b-poly(lactide-co-glycolide) is a functionalized, amphiphilic, diblock copolymer composed of a hydrophilic PEG block and a hydrophobic PLGA block. These biodegradable, biocompatible polymers can self-assemble to form nanoparticles, such as micelles and polymersomes, in both aqueous and non-aqueous media. Due to these properties, these polymers are widely used in polymeric nanoparticle formulation to achieve controlled and targeted delivery of therapeutic agents (e.g. APIs, genetic material, peptides, vaccines, and antibiotics). The folate functional group on the PEG chain enables rapid and facile surface functionalization, allowing for these materials to be used in applications such as targeted drug delivery.
Codice della classe di stoccaggio
13 - Non Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
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