776181

3-(2-Acetoxy-4,6-dimethylphenyl)-3-methylbutyric acid N-succinimidyl ester

95%

• Sinonimo/i: 3-(2-Acetoxy-4,6-dimethylphenyl)-3-methylbutyric acid N-hydroxysuccinimide ester, Trimethyl lock NHS, Trimethyl lock succinimidyl ester
• Formula empirica (notazione di Hill): C₁₉H₂₃NO₆
• Peso molecolare: 361.39
• Numero MDL: MFCD24386387
• Codice UNSPSC: 12352106
• ID PubChem: 329767818
• NACRES: NA.22

Proprietà

• Saggio: 95%
• Forma fisica: solid
• Punto di fusione: 107-112 °C
• Temperatura di conservazione: 2-8°C
• Stringa SMILE: CC(=O)Oc1cc(C)cc(C)c1C(C)(C)CC(=O)ON2C(=O)CCC2=O
• InChI: 1S/C19H23NO6/c1-11-8-12(2)18(14(9-11)25-13(3)21)19(4,5)10-17(24)26-20-15(22)6-7-16(20)23/h8-9H,6-7,10H2,1-5H3; KMNOKEFBKJGRFL-UHFFFAOYSA-N

Descrizione

Applicazioni

This ′trimethyl lock′ derivative is activated with a succinimidyl ester for modification of amine containing compounds and biomolecules. After modification of your amine of interest, your now ′masked′ molecule can be released by cleavage of the ester, which can be achieved by cellular esterases. This triggers a rapid lactonization reaction of the ′trimethyl lock′ to regenerate your original amine-containing molecule. This approach has been applied to release of fluorophores, peptides, nucleic acids as well as small molecule drugs.

Informazioni sulla sicurezza

• Pittogrammi: GHS07
• Avvertenze: Warning
• Indicazioni di pericolo: H302
• Classi di pericolo: Acute Tox. 4 Oral
• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable