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765457

Sigma-Aldrich

Gold nanoparticles

10 nm diameter, carboxylic acid functionalized, PEG 3000, OD 50, dispersion in H2O

Sinonimo/i:

Gold nanoparticles COOH functionalized, Au NP COOH, Gold Colloid

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About This Item

Codice UNSPSC:
12162002
NACRES:
NA.23

Materiali

PEG 3000

Stato

dispersion in H2O
nanoparticles

Confezionamento

glass bottle of 1 mL

OD

50

Diametro

10 nm

pH

6.0-8.0 (25 °C)

Solubilità

water: miscible

Densità

1.00 g/cm3

λmax

520 nm

Gruppo funzionale

carboxylic acid

Temperatura di conservazione

2-8°C

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Categorie correlate

Descrizione generale

Carboxylic acid functionalized GNPs form conjugates with various protein molecules due to the electrostatic attraction between negatively charged carboxylate groups and positively charged amino groups of protein.

Applicazioni

Carboxylic acid functionalized, PEG 3000, OD 50, and H2O dispersed gold nanoparticles (10 nm) (AuNPs) can be potentially used in the development of biosensors, cancer-cell imaging, drug delivery, and photothermal therapy. AUNPs may also be used in the immobilization of antibodies to improve the sensitivity of optical fiber sensors for the screening of COVID-19. It can also be deposited on the titanium electrode for the formation of a miniaturized device for the electrochemical detection of DNA hybridization.
Functionalized Particles have been extensively used to study cellular uptake of nanoparticles and targeted drug delivery.
The carboxylic acid group binds with various proteins and is used in targeted drug delivery and gene therapy.

Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

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Certificati d'analisi (COA)

Lot/Batch Number
MKCP7677
MKCM4667
MKBZ8814V
MKBN9349V
MKBL5789V

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I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.

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Optical Fiber Sensors for Rapid Screening of COVID-19
Nag P, et al.
Transactions of the Indian National Academy of Engineering, 6, 1-4 (2020)
Size-dependent in vivo toxicity of PEG-coated gold nanoparticles
Zhang X, et al.
International journal of nanomedicine, 6, 2071-2071 (2011)
Nishima Wangoo et al.
Journal of colloid and interface science, 323(2), 247-254 (2008-05-20)
We report a novel strategy for the synthesis of aqueous stable, carboxylated gold nanoparticles (GNPs) by using glutamic acid as the reducing agent. The ratio of chloroaurate ions, AuCl(-)(4) to glutamic acid was optimized in the reaction medium to obtain
Functionalized gold nanoparticles and their biomedical applications
Tiwari, P. M., Vig, K., Dennis, V. A., & Singh, S. R.
Nanomaterials, 1(1), 31-63 (2011)

Articoli

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The recent emergence of a number of highly functional nanomaterials has enabled new approaches to the understanding, diagnosis, and treatment of cancer.

Micro- and Nanofabricated Biomaterials for the Study of Cells and Microtissues

Biomaterials science involves the design and fabrication of smart materials for studying, directing, or mimicking biology. For successful integration of biomaterials in biological research, a meaningful understanding of biological systems is required.

Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..

Contatta l'Assistenza Tecnica.