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732613

Sigma-Aldrich

Poly(ethylene glycol) methyl ether

average MN 20,000, methoxy, hydroxyl

Sinonimo/i:

Polyethylene glycol monomethyl ether

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About This Item

Formula condensata:
CH3(OCH2CH2)nOH
Numero CAS:
9004-74-4
Numero MDL:
MFCD00084416
Codice UNSPSC:
12162002
NACRES:
NA.23

Nome del prodotto

Poly(ethylene glycol) methyl ether, average Mn 20,000

Densità del vapore

>1 (vs air)

Tensione di vapore

0.05 mmHg ( 20 °C)

Stato

powder or crystals

PM

average Mn 20,000

Punto di fusione

64-69 °C

Mw/Mn

≤1.2

Estremità Ω

hydroxyl

Estremità α

methoxy

Temperatura di conservazione

−20°C

Stringa SMILE

O(CCO)C

InChI

1S/C3H8O2/c1-5-3-2-4/h4H,2-3H2,1H3
XNWFRZJHXBZDAG-UHFFFAOYSA-N

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Applicazioni

  • Deoxycholic acid-grafted PEGylated chitosan micelles for the delivery of mitomycin C.: This study develops PEGylated chitosan micelles grafted with deoxycholic acid for effective delivery of mitomycin C, showcasing the potential of PEGylated compounds in pharmaceutical formulations and drug delivery systems (Zhang et al., 2015).

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

359.6 °F

Punto d’infiammabilità (°C)

182 °C

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Certificati d'analisi (COA)

Lot/Batch Number
MKCQ4514
MKCM1673
MKCL2175
MKCK9517
MKCH9258

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Poly(ethylene glycol) methyl ether BioUltra, 500

Sigma-Aldrich

71578

Poly(ethylene glycol) methyl ether

Methoxypolyethylene glycol 350 average mol wt 350

Sigma-Aldrich

M6768

Methoxypolyethylene glycol 350

Poli(etilenglicole) 20000 (stabilised) for synthesis

Sigma-Aldrich

8.18897

Poli(etilenglicole)

Poli(etilenglicole) BioUltra, 20,000

Sigma-Aldrich

95172

Poli(etilenglicole)

Robert K Delong et al.
Nanomedicine (London, England), 7(12), 1851-1862 (2012-09-05)
Nanoparticle conjugates have the potential for delivering siRNA, splice-shifting oligomers or nucleic acid vaccines, and can be applicable to anticancer therapeutics. This article compares tripartite conjugates with gold nanoparticles or synthetic methoxypoly(ethylene glycol)-block-polyamidoamine dendrimers. Interactions with model liposomes of a
Smita K Pawar et al.
International journal of pharmaceutics, 436(1-2), 183-193 (2012-06-23)
Efficacy of anticancer drug is limited by the severe adverse effects induced by drug; therefore the crux is in designing delivery systems targeted only to cancer cells. Toward this objectives, we propose, synthesis of poly(ethylene glycol) (PEG)-doxorubicin (DOX) prodrug conjugates
Prakash G Avaji et al.
Bioorganic & medicinal chemistry letters, 23(6), 1763-1767 (2013-02-16)
Saturated fatty acids (FA) were grafted using tyrosine as a spacer group to the cyclotriphosphazene ring along with equimolar hydrophilic methoxy poly(ethylene glycol) (MPEG) in cis-nongeminal way. Seven new cyclotriphosphazene amphiphiles were prepared from combinations of hydrophilic MPEGs with different
Jiani Zheng et al.
Langmuir : the ACS journal of surfaces and colloids, 28(37), 13261-13273 (2012-08-28)
Alginate/chitosan/alginate (ACA) hydrogel microcapsules were modified with methoxy poly(ethylene glycol) (MPEG) to improve protein repellency and biocompatibility. Increased MPEG surface graft density (n(S)) on hydrogel microcapsules was achieved by controlling the grafting parameters including the buffer layer substrate, membrane thickness
Mulu Z Tesfay et al.
Journal of virology, 87(7), 3752-3759 (2013-01-18)
We are developing oncolytic vesicular stomatitis viruses (VSVs) for systemic treatment of multiple myeloma, an incurable malignancy of antibody-secreting plasma cells that are specifically localized in the bone marrow. One of the presumed advantages for using VSV as an oncolytic
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Articoli

Degradable Poly(ethylene glycol) Hydrogels for 2D and 3D Cell Culture

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.

Versatile Cell Culture Scaffolds via Bio-orthogonal Click Reactions

Devising biomaterial scaffolds that are capable of recapitulating critical aspects of the complex extracellular nature of living tissues in a threedimensional (3D) fashion is a challenging requirement in the field of tissue engineering and regenerative medicine.

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