636010

3,5-Dimethylpyrazole-4-boronic acid pinacol ester

97%

• Sinonimo/i: 3,5-Dimethyl-4-(4,4,5,5-tetramethyl-1,3,2dioxaborolan-2-yl)-1H-pyrazole, 3,5-Dimethyl-4-pyrazoleboronic acid pinacol ester
• Formula empirica (notazione di Hill): C₁₁H₁₉BN₂O₂
• Numero CAS: 857530-80-4
• Peso molecolare: 222.09
• Numero MDL: MFCD05663852
• Codice UNSPSC: 12352103
• ID PubChem: 24882751
• NACRES: NA.22

Proprietà

• Livello qualitativo: 100
• Saggio: 97%
• Stato: solid
• Punto di fusione: 163-168 °C (lit.)
• Stringa SMILE: Cc1n[nH]c(C)c1B2OC(C)(C)C(C)(C)O2
• InChI: 1S/C11H19BN2O2/c1-7-9(8(2)14-13-7)12-15-10(3,4)11(5,6)16-12/h1-6H3,(H,13,14); GNUDAJTUCJEBEI-UHFFFAOYSA-N

Descrizione

Applicazioni

3,5-Dimethylpyrazole-4-boronic acid pinacol ester can be used:

• To synthesize 9H-pyrimido[4,5-b]indole and aryl-benzimidazole based BET bromodomain and extra terminal (BET) protein inhibitors.
• To prepare naphthalimide based photo-exchangeable photochromic fluorescent molecules.
• As a reactant to develop DNA-encoded chemical libraries by palladium-catalyzed Suzuki coupling reaction with DNA-linked aryl halides.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Dispositivi di protezione individuale: dust mask type N95 (US), Eyeshields, Gloves