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422967

Sigma-Aldrich

4-Aminothiophenol

≥97.0%

Sinonimo/i:

4-Aminobenzenethiol, 4-Aminophenyl mercaptan, 4-Mercaptoaniline

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About This Item

Formula condensata:
H2NC6H4SH
Numero CAS:
1193-02-8
Peso molecolare:
125.19
Beilstein:
906904
Numero CE:
214-763-4
Numero MDL:
MFCD00007880
Codice UNSPSC:
12352100
ID PubChem:
24866468
NACRES:
NA.22

Saggio

≥97.0%

P. eboll.

140-145 °C/16 mmHg (lit.)

Punto di fusione

37-42 °C (lit.)

Temperatura di conservazione

2-8°C

Stringa SMILE

Nc1ccc(S)cc1

InChI

1S/C6H7NS/c7-5-1-3-6(8)4-2-5/h1-4,8H,7H2
WCDSVWRUXWCYFN-UHFFFAOYSA-N

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Descrizione generale

4-Aminothiophenol is a bifunctional aromatic thiol used to form self-assembled monolayers for biosensors.

4-Aminothiophenol (p-aminothiophenol, PATP) is an aromatic thiol. The self-assembly of silver and gold nano particles which are interconnected with 4-ATP to form metal-molecule-metal sandwich architecture has been characterized by surface enhanced Raman scattering (SERS) using an off-surface plasmon resonance condition. Chemical transformation of PATP to 4,4-dimercaptoazobenzene (DMAB) has been extensively studied.

Applicazioni

4-Aminothiophenol (4-ATP) was employed as bifunctional molecule to functionalize gold nanoparticles (NPs) used in surface-enhanced Raman spectroscopy (SERS) detection of thrombin by protein recognition.

It may be used in the following studies:
  • As a water insoluble ligand in the synthesis of pectin–4-aminothiophenol conjugates.
  • To functionalize gold nanorods (GNR) in the development of GNR nitrite sensor.
  • To form self-assembled monolayers (SAMs) of 4-aminothiophenol in the development of DNA biosensor.
  • As a linker to thiol (SH) functionalize multiwalled carbon nanotubes (MWCNTs).
  • To generate amino terminated self-assembly monolayers(SAMs) on platinum electrode which forms the base for attachment of single-wall carbon nano tubes (SWCTs).

Pittogrammi

Corrosion
GHS05

Avvertenze

Danger

Indicazioni di pericolo

H314

Classi di pericolo

Skin Corr. 1B

Codice della classe di stoccaggio

8A - Combustible corrosive hazardous materials

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

235.4 °F - closed cup

Punto d’infiammabilità (°C)

113 °C - closed cup

Dispositivi di protezione individuale

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

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Certificati d'analisi (COA)

Lot/Batch Number
0000219044
0000164217
0000120950
BCCD5102
0000085804

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Sigma-Aldrich

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Application of coulometric FFT cyclic voltammetry for determination of cholesterol based on cholesterol oxidase nano-biosensor.
Norouzi P.
Analytical and Bioanalytical Electrochemistry, 4(1), 70-82 (2010)
The Fault in Their Shapes: Investigating the Surface-Plasmon-Resonance-Mediated Catalytic Activities of Silver Quasi-Spheres, Cubes, Triangular Prisms, and Wires.
da Silva AGM, et al.
Langmuir, 31(37), 10272-10278 (2015)
Effect of aqueous and ambient atmospheric environments on plasmon-driven selective reduction reactions.
Ding Q, et al.
Scientific Reports, 5 (2015)
4-Aminothiophenol Self-Assembled Monolayer for the Development of a DNA Biosensor Aiming the Detection of Cylindrospermopsin Producing Cyanobacteria.
Valerio E, et al.
Electroanalysis, 20(22), 2467-2474 (2008)
SERS detection of thrombin by protein recognition using functionalized gold nanoparticles.
Bizzarri AR, et al.
Nanomedicine: Nanotechnology, Biology, and Medicine, 3(4), 306-310 (2007)
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