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415464

Sigma-Aldrich

N-Vinylcaprolactam

98%, stabilized

Sinonimo/i:

1-Ethenylazepan-2-one, 1-Ethenylhexahydro-2H -azepin-2-one, 1-Vinylazepan-2-one

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About This Item

Formula empirica (notazione di Hill):
C8H13NO
Numero CAS:
2235-00-9
Peso molecolare:
139.19
Numero CE:
218-787-6
Numero MDL:
MFCD00080693
Codice UNSPSC:
12162002
ID PubChem:
24866004
NACRES:
NA.23

Saggio

98%

Stato

solid

contiene

~20 ppm HO-TEMPO as stabilizer

P. ebollizione

128 °C/21 mmHg (lit.)

Punto di fusione

35-38 °C (dec.) (lit.)

Densità

1.029 g/mL at 25 °C (lit.)

Temperatura di conservazione

2-8°C

Stringa SMILE

C=CN1CCCCCC1=O

InChI

1S/C8H13NO/c1-2-9-7-5-3-4-6-8(9)10/h2H,1,3-7H2
JWYVGKFDLWWQJX-UHFFFAOYSA-N

Categorie correlate

Descrizione generale

N-Vinylcaprolactam (NVCL) is an organo-soluble amphiphilic material that is soluble in solvents like benzene, isobutanol, and isopropanol. It can be used in the preparation of poly(NVCL) by free-radical polymerization at a temperature higher than its melting point.

Applicazioni

NVCL forms a temperature responsive polymer, which can be used for a variety of biomedical applications.

Pittogrammi

Health hazardExclamation mark
GHS08,GHS07

Avvertenze

Danger

Indicazioni di pericolo

H302 + H312,H317,H319,H372

Classi di pericolo

Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Sens. 1 - STOT RE 1

Organi bersaglio

Liver,Upper respiratory tract

Codice della classe di stoccaggio

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

213.8 °F - closed cup

Punto d’infiammabilità (°C)

101 °C - closed cup

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves

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Certificati d'analisi (COA)

Lot/Batch Number
STBH7199
STBH6746
STBH6227
STBH5711
STBH5316

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Sigma-Aldrich

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Synthesis of N-vinylcaprolactam polymers in water-containing media
Lozinsky VI, et al.
Polymer, 41(17), 6507-6518 (2000)
Oleksandra Zavgorodnya et al.
Journal of colloid and interface science, 506, 589-602 (2017-08-02)
We report nanothin temperature-responsive hydrogel films of poly(N-vinylcaprolactam) nanoparticles (νPVCL) with remarkably high loading capacity for topical drug delivery. Highly swollen (νPVCL)
Simone F Medeiros et al.
Drug development and industrial pharmacy, 43(9), 1519-1529 (2017-04-25)
Poly(N-vinylcaprolactam) (PNVCL) and poly(N-vinylcaprolactam-co-acrylic acid) (poly(NVCL-co-AA)) were synthesized by solution-free radical polymerization and displayed thermo-responsive behavior, with lower critical solution temperatures (LCSTs) of 35 °C and 39 °C, respectively. The incorporation of AA unities made the poly(NVCL-co-AA) sensitive to both pH and
Poly (N-vinylcaprolactam), a comprehensive review on a thermoresponsive polymer becoming popular
Cortez-Lemus NA and Licea-Claverie A
Progress in Polymer Science, 53(5), 1-51 (2016)
Serap Durkut et al.
Artificial cells, nanomedicine, and biotechnology, 45(8), 1665-1674 (2017-01-13)
In this study, we synthesized poly(N-vinylcaprolactam)-g-collagen (PNVCL-g-Col) by grafting collagen with carboxyl group-terminated thermosensitive PNVCL-COOH. The resulting biopolymer was evaluated for its structural, thermal, and rheological properties. Aqueous solutions of PNVCL-g-Col exhibited a temperature-dependent phase transition around human physiological temperature
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