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247480

Sigma-Aldrich

Domiphen bromide

97%

Sinonimo/i:

(Dodecyldimethyl-2-phenoxyethyl)ammonium bromide

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About This Item

Formula condensata:
CH3(CH2)11N(CH3)2(CH2CH2OC6H5)Br
Numero CAS:
538-71-6
Peso molecolare:
414.46
Numero CE:
208-702-0
Numero MDL:
MFCD00011769
Codice UNSPSC:
12352112
ID PubChem:
24854870
NACRES:
NA.22

Saggio

97%

Forma fisica

powder

Punto di fusione

117-119 °C (lit.)

Stringa SMILE

[Br-].CCCCCCCCCCCC[N+](C)(C)CCOc1ccccc1

InChI

1S/C22H40NO.BrH/c1-4-5-6-7-8-9-10-11-12-16-19-23(2,3)20-21-24-22-17-14-13-15-18-22;/h13-15,17-18H,4-12,16,19-21H2,1-3H3;1H/q+1;/p-1
OJIYIVCMRYCWSE-UHFFFAOYSA-M

Descrizione generale

Domiphen bromide (DMP) is a quaternary ammonium compound that belongs to the class of phenol ethers. It can be used as a cationic surfactant.

Applicazioni

  • Domiphen Bromide in Antimicrobial Applications: A clinical trial assessed the effectiveness of a mouthwash containing Domiphen Bromide among other quaternary ammonium compounds, showcasing its ability to significantly reduce gingivitis, supporting its use in dental health products (Rosa and Sturzenberger, 1976).
  • Toxicity and Safety Profile of Domiphen Bromide: A recent study explored the proarrhythmic effects induced by Domiphen Bromide in both in vitro and in vivo models, providing vital safety information crucial for its use in pharmaceutical applications (Long et al., 2021).

Pittogrammi

Exclamation mark
GHS07

Avvertenze

Warning

Indicazioni di pericolo

H302,H315,H319,H335

Classi di pericolo

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organi bersaglio

Respiratory system

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Triton™ X-100 laboratory grade

Sigma-Aldrich

X100

Triton™ X-100

F Scaglione et al.
International journal of clinical pharmacology research, 3(4), 261-264 (1983-01-01)
By means of a double blind, placebo controlled trial, we have studied 29 patients (14 M and 15 F) affected by different acute infectious oral diseases. Our results suggest that domifen bromide may be useful in treating infectious oral diseases
[Antiseptic activity of domiphen bromide on the yeast Candida in the mouth].
P Goumas et al.
Stomatologia, 41(5), 249-257 (1984-09-01)
Lorenzo H Chen et al.
Journal of pharmaceutical and biomedical analysis, 40(4), 964-970 (2005-10-26)
This report describes a rapid and accurate reversed phase HPLC method for the simultaneous quantitation of multiple surfactants in various bioprocess solution matrices including cell lysates. Separation and quantitation of a mixture of the cationic detergent domiphen bromide from the
F Scaglione et al.
International journal of clinical pharmacology research, 3(5), 357-361 (1983-01-01)
Thirty-one patients (21 M and 10 F), affected by acute infectious dental disease, were treated with domifen bromide (A) or placebo (Pl). It was found that A had a beneficial effect on the results of clinical controls and reduced the
Separation of fulvic acid from soil extracts based on ion-pair formation with a cationic surfactant
Fukushima M, et al.
Analytical Sciences, 22(2), 229-233 (2006)
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