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148776

Sigma-Aldrich

3-Hydroxyanthranilic acid

97%, for peptide synthesis

Sinonimo/i:

2-Amino-3-hydroxybenzoic acid

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About This Item

Formula condensata:
HOC6H3(NH2)CO2H
Numero CAS:
548-93-6
Peso molecolare:
153.14
Numero CE:
208-962-5
Numero MDL:
MFCD00007700
Codice UNSPSC:
12352106
ID PubChem:
24848918
NACRES:
NA.22

product name

3-Hydroxyanthranilic acid, 97%

Livello qualitativo

200

Saggio

97%

Forma fisica

solid

Impiego in reazioni chimiche

reaction type: solution phase peptide synthesis

Punto di fusione

240 °C (dec.) (lit.)

applicazioni

peptide synthesis

Stringa SMILE

Nc1c(O)cccc1C(O)=O

InChI

1S/C7H7NO3/c8-6-4(7(10)11)2-1-3-5(6)9/h1-3,9H,8H2,(H,10,11)
WJXSWCUQABXPFS-UHFFFAOYSA-N

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Descrizione generale

3-Hydroxyanthranilic acid is an aminobenzoic acid commonly used as an intermediate in various chemical reactions.

Applicazioni

<ul>
<li><strong>Direct enzyme inhibition to mitigate quinolinic acid formation:</strong> Used to synthesize 2-amino-3-carboxymuconic semialdehyde (ACMS) during the kynurenine pathway of Tryptophan catabolism (Sanz et al., 2022).</li>
</ul>

Pittogrammi

Health hazardExclamation mark
GHS08,GHS07

Avvertenze

Warning

Classi di pericolo

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organi bersaglio

Respiratory system

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves

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Certificati d'analisi (COA)

Lot/Batch Number
0000276402
0000276402
SLCK0194
SLCG1067
SLCB1339

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Neurochemical research, 35(9), 1315-1322 (2010-05-22)
Post-stroke inflammation may induce upregulation of the kynurenine (KYN) pathway for tryptophan (TRP) oxidation, resulting in neuroprotective (kynurenic acid, KA) and neurotoxic metabolites (3-hydroxyanthranillic acid, 3-HAA). We investigated whether activity of the kynurenine pathway in acute ischemic stroke is related
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