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Merck

MYC

v-myc avian myelocytomatosis viral oncogene homolog

Sinonimi:
MRTL, MYCC, bHLHe39, c-Myc
Specie:
Human MYC (4609), Mouse Myc (17869), Rat Myc (24577), chicken MYC (420332), dog MYC (403924), domestic cat MYC (100379628), cow MYC (511077), domestic guinea pig Myc (100724557), Domestic Rabbit MYC (100327265), sheep MYC (443447)
ID UniProtKB:
P01106, A8WFE7, P01107, Q14026
ID gene:
  • Human(4609) Summary: The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. [provided by RefSeq, Jul 2008]
  • Mouse(17869) myelocytomatosis oncogene
  • Rat(24577) myelocytomatosis oncogene
  • chicken(420332) v-myc myelocytomatosis viral oncogene homolog
  • dog(403924) v-myc myelocytomatosis viral oncogene homolog (avian)
  • domestic cat(100379628) v-myc myelocytomatosis viral oncogene homolog (avian)
  • cow(511077) v-myc myelocytomatosis viral oncogene homolog (avian)
  • domestic guinea pig(100724557) v-myc myelocytomatosis viral oncogene homolog (avian)
  • Domestic Rabbit(100327265) v-myc myelocytomatosis viral oncogene homolog (avian)
  • sheep(443447) v-myc myelocytomatosis viral oncogene homolog (avian)

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ELISA

N° Catalogo
Descrizione
Specie
RAB1379
Human c-Myc ELISA, for serum, plasma and cell culture supernatants,
Specie
human

Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
SAB4702005
Monoclonal Anti-c-Myc tag Biotin produced in mouse, ,
Reattività con
Applicazione
flow cytometry
immunohistochemistry
immunoprecipitation (IP)
western blot
M4439
Anticorpi anti-c-Myc, monoclonali, murini, clone 9E10, purified from hybridoma cell culture,
Reattività con
human
Applicazione
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
microarray
western blot
05-724
Anticorpo anti-tag Myc, clone 4A6, clone 4A6, Upstate®, from mouse,
Reattività con
human
Applicazione
ChIP
immunocytochemistry
immunofluorescence
immunoprecipitation (IP)
western blot
C3956
Anti-c-Myc antibody produced in rabbit, ~0.5 mg/mL, affinity isolated antibody, buffered aqueous solution,
Reattività con
human
Applicazione
immunocytochemistry
immunofluorescence
immunoprecipitation (IP)
microarray
western blot
05-724MG
Anti-Myc Tag Antibody, clone 4A6, clone 4A6, Upstate®, from mouse,
Reattività con
human
Applicazione
immunocytochemistry
immunofluorescence
immunoprecipitation (IP)
western blot

Proteins

N° Catalogo
Descrizione
Specie
SRP2089
C-myc, proto oncogene human, recombinant, expressed in E. coli, ≥80% (SDS-PAGE),
Specie
human

esiRNA

N° Catalogo
Descrizione
Specie
EHU021051
MISSION® esiRNA, targeting human MYC,
Specie
human
EMU075291
MISSION® esiRNA, targeting mouse Myc,
Specie
mouse