LRP6
low density lipoprotein receptor-related protein 6
Sinonimi:
ADCAD2
Specie:
Human LRP6 (4040), Mouse Lrp6 (16974), Rat Lrp6 (312781), Zebrafish lrp6 (100003877), chicken LRP6 (419097), dog LRP6 (477692), domestic cat LRP6 (101082246), Horse LRP6 (100063409), cow LRP6 (536328), sheep LRP6 (101112971) ...Più
ID UniProtKB:
ID gene:
- Human(4040) Summary: This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined.[provided by RefSeq, Dec 2009]
- Mouse(16974) low density lipoprotein receptor-related protein 6
- Rat(312781) low density lipoprotein receptor-related protein 6
- Zebrafish(100003877) low-density lipoprotein receptor-related protein 6
- chicken(419097) low density lipoprotein receptor-related protein 6
- dog(477692) low density lipoprotein receptor-related protein 6
- domestic cat(101082246) low density lipoprotein receptor-related protein 6
- Horse(100063409) low density lipoprotein receptor-related protein 6
- cow(536328) low density lipoprotein receptor-related protein 6
- sheep(101112971) low density lipoprotein receptor-related protein 6
- domestic guinea pig(100735282) low density lipoprotein receptor-related protein 6
- naked mole-rat(101703711) low density lipoprotein receptor-related protein 6
- Domestic Rabbit(100352000) low density lipoprotein receptor-related protein 6
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Antibodies
N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-LRP6, clone A59, Ectodomain Antibody, clone A59, from mouse,
Reattività con
human
Applicazione
flow cytometry
immunocytochemistry
immunoprecipitation (IP)
immunocytochemistry
immunoprecipitation (IP)
Anti-LRP6 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunohistochemistry
Anti-phospho-LRP-6 (Thr1479), from rabbit,
Reattività con
human, mouse, rhesus monkey
Applicazione
inhibition assay
western blot
western blot
Anti-LRP6 Antibody, clone 1C10, clone 1C10, from mouse,
Reattività con
human, mouse, rat
Applicazione
immunoprecipitation (IP)
western blot
western blot
Anti-LRP6 Antibody, clone 1D11 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reattività con
bovine, canine, feline, horse, human, monkey, mouse, porcine, rat
Applicazione
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot