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Merck

ADORA3

adenosine A3 receptor

Sinonimi:
A3AR, AD026, bA552M11.5
Specie:
ID UniProtKB:
ID gene:
  • Human(140) Summary: This gene encodes a protein that belongs to the family of adenosine receptors, which are G-protein-coupled receptors that are involved in a variety of intracellular signaling pathways and physiological functions. The receptor encoded by this gene mediates a sustained cardioprotective function during cardiac ischemia, it is involved in the inhibition of neutrophil degranulation in neutrophil-mediated tissue injury, it has been implicated in both neuroprotective and neurodegenerative effects, and it may also mediate both cell proliferation and cell death. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(11542) adenosine A3 receptor
  • Rat(25370) adenosine A3 receptor
  • chicken(373956) adenosine A3 receptor
  • domestic cat(101094689) adenosine A3 receptor
  • dog(403805) adenosine A3 receptor
  • cow(780806) adenosine A3 receptor
  • sheep(443330) adenosine A3 receptor
  • Domestic Rabbit(100008725) adenosine A3 receptor
  • naked mole-rat(101697269) adenosine A3 receptor
  • domestic guinea pig(100725432) adenosine A3 receptor

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Small Molecule - Agonist

N° Catalogo
Descrizione
Specie
Adenosine, ,
Specie
human
Formycin A, from Streptomyces kaniharaensis, ≥98% (HPLC),
Specie
human
Adenosine, United States Pharmacopeia (USP) Reference Standard,
Specie
human
Adenosine, phyproof® Reference Substance,
Specie
human
Adenosine, Pharmaceutical Secondary Standard; Certified Reference Material,
Specie
human

Small Molecule - Antagonist

N° Catalogo
Descrizione
Specie
VUF 5574, ,
Specie
human
Tyramine hydrochloride, ≥98%,
Specie
human
(S)-(−)-Bay K8644, ≥98% (HPLC), solid,
Specie
human, rat
3-Deazaadenosine, ,
Specie
rat
Caffeina, United States Pharmacopeia (USP) Reference Standard,
Specie
human

Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-Adenosine A3 Receptor Antibody, extracellular (a.a. 154-168), Chemicon®, from rabbit,
Reattività con
rat
Applicazione
ELISA
immunocytochemistry

western blot
Monoclonal Anti-ADORA3 antibody produced in mouse, clone 1A3, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
Anti-ADORA3 antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
ELISA
immunofluorescence

Small Molecule - Inhibitor

N° Catalogo
Descrizione
Specie
EHNA hydrochloride, ≥98% (HPLC),
Specie
human
Dilazep dihydrochloride, powder,
Specie
human
5′-Deoxy-5′-(methylthio)adenosine, ,
Specie
human, rat, mouse
α-Naphthoflavone, ≥98%,
Specie
human, rat
Galangin, autophagy inducing flavonoid,
Specie
human, rat

Small Molecule - Ligand

N° Catalogo
Descrizione
Specie
2-Chloro-2′-deoxyadenosine, antileukemic,
Specie
rat, human
1,7-Dimethylxanthine, ~98%, solid,
Specie
rat, human
Chloro-IB-MECA, solid, ≥98% (HPLC),
Specie
human, rat
Adenosine, ≥99%,
Specie
human, rat
Theophylline, anhydrous, ≥99%, powder,
Specie
mouse, human, rat

Small Molecule - Mixed Agonist/Antagonist

N° Catalogo
Descrizione
Specie
2-Iodoadenosine, 97%,
Specie
human, rat
2-Fluoroadenine-9-β-D-arabinofuranoside, DNA synthesis and methylation inhibitor,
Specie
rat, human
2-Fluoroadenosine, 97%,
Specie
rat, human
2-Chloroadenosine, ,
Specie
human, rat
Chloro-IB-MECA, solid, ≥98% (HPLC),
Specie
human, rat

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting human ADORA3,
Specie
human
MISSION® esiRNA, targeting human TMIGD3,
Specie
human