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Key Documents

RAB0007

Sigma-Aldrich

Human RAGE / AGER ELISA Kit

for serum, plasma, cell culture supernatant and urine

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About This Item

Code UNSPSC :
41116158
Nomenclature NACRES :
NA.32

Espèces réactives

human

Conditionnement

kit of 96 wells (12 strips x 8 wells)

Technique(s)

ELISA: suitable
capture ELISA: suitable

Entrée

sample type cell culture supernatant(s)
sample type plasma
sample type serum
sample type urine

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 3 pg/mL
standard curve range: 2.06-1500 pg/mL

Méthode de détection

colorimetric

Conditions d'expédition

wet ice

Température de stockage

−20°C

Informations sur le gène

human ... AGER(177)

Catégories apparentées

Description générale

The Human RAGE ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human RAGE in serum, plasma, cell culture supernatants and urine.

Immunogène

Recombinant Human RAGE

Application

For research use only. Not for use in diagnostic procedures.

Human RAGE / AGER ELISA kit has been used for the quantitative measurement of RAGE in cerebrospinal fluid.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Actions biochimiques/physiologiques

Advanced glycosylation end-product specific receptor (AGER) or RAGE is part of the immunoglobulin superfamily of cell surface molecules. The soluble form of the protein has a function in the Wnt pathway. RAGE has a role in the development of inflammatory and cellular damage, as well as cellular toxicity. It has been associated with diabetic atherosclerosis. AGER/RAGE also modulates cell proliferation, differentiation and apoptosis.(6}

Autres remarques

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

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Pictogrammes

Corrosion
GHS05

Mention d'avertissement

Warning

Mentions de danger

H290

Conseils de prudence

P234 - P390

Classification des risques

Met. Corr. 1

Code de la classe de stockage

8A - Combustible corrosive hazardous materials

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

An inverse association between serum soluble receptor of advanced glycation end products and hyperandrogenism and potential implication in polycystic ovary syndrome patients
Yu Liao
Reproductive Biology and Endocrinology, 15, 9-9 (2017)
Increase of Soluble RAGE in Cerebrospinal Fluid following Subarachnoid Haemorrhage
Bartosz Sokol
BioMed Research International (2017)
Association of Polymorphisms of the Receptor for Advanced Glycation Endproducts Gene with Schizophrenia in a Han Chinese Population
Jiawu Fu
Biomedical Research, 6379639-6379639 (2017)
Association of RAGE gene Gly82Ser polymorphism with coronary artery disease and ischemic stroke
Wen-Qi Ma
Medicine, 95(49), e5593-e5593 (2016)
Zhi-hong Wang et al.
Molecular nutrition & food research, 58(7), 1426-1435 (2014-03-04)
Antiglycative effects of glycyrrhizic acid (GA) in kidney of diabetic mice were examined. GA at 0.05, 0.1, and 0.2% was supplied to diabetic mice for 9 wk. Results showed that GA intake increased its deposit in kidney, raised plasma insulin
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