E5750

Ergocalciferol

40,000,000 USP units/g

• Synonyme(s) : Ergocalciférol, Ergostérol irradié, « Ergostérol irradié »
• Formule empirique (notation de Hill) : C₂₈H₄₄O
• Numéro CAS: 50-14-6
• Poids moléculaire : 396.65
• Beilstein: 1916682
• Numéro CE : 200-014-9
• Numéro MDL: MFCD00166988
• Code UNSPSC : 12352205
• eCl@ss : 34058017
• ID de substance PubChem : 24894344
• Nomenclature NACRES : NA.79

Propriétés

• Source biologique: synthetic (organic)
• Niveau de qualité: 200
• Essai: ≥97%
• Forme: powder
• Activité spécifique: 40,000,000 USP units/g
• Technique(s): HPLC: suitable
• Couleur: white to off-white
• Pf: 114-118 °C (lit.)
• Température de stockage: 2-8°C
• Chaîne SMILES: CC(C)[C@@H](C)/C=C/[C@@H](C)[C@@]1([H])CC[C@@]([C@]1(C)CCC/2)([H])C2=C\C=C(C[C@@H](O)CC3)/C3=C
• InChI: 1S/C28H44O/c1-19(2)20(3)9-10-22(5)26-15-16-27-23(8-7-17-28(26,27)6)12-13-24-18-25(29)14-11-21(24)4/h9-10,12-13,19-20,22,25-27,29H,4,7-8,11,14-18H2,1-3,5-6H3/b10-9+,23-12+,24-13-/t20-,22+,25-,26+,27-,28+/m0/s1
• Clé InChI: MECHNRXZTMCUDQ-RKHKHRCZSA-N
• Informations sur le gène: human ... VDR(7421)

Description

Description générale

Vitamin D₂ or ergocalciferol is available through dietary supplements or plant sources. It is a provitamin, which is fat-soluble.

Application

Ergocalciferol has been used as a component of the diet for rats, to study its bioavailability from ultraviolet-irradiated D2-rich yeast. It has also been used as a standard for identification and quantification of vitamins, as part of a study to determine the nutritional composition of food fishes.

Actions biochimiques/physiologiques

Ergocalciferol (vitamin D₂) and 25-Hydroxycholecalciferol (vitamin D₃) are the two forms of vitamin D, which are activated in vivo by hydroxylation. Vitamin D2 and D3 may be used in a wide range of studies to assess their effects on function such as immune function and calcium homeostasis.

Ergocalciferol is used for antirachitic treatment. Vitamin D has an active role in bone mineralization. Severe deficiency of this vitamin has been associated with osteomalacia and rickets.

Conditionnement

Sealed ampule.

Quantité

1 USP unit = 1 I.U.

Informations sur la sécurité

• Pictogrammes: GHS06,GHS08
• Mention d'avertissement: Danger
• Mentions de danger: H301 + H311,H330,H372
• Conseils de prudence: P260 - P264 - P280 - P302 + P352 + P312 - P304 + P340 + P310 - P314
• Classification des risques: Acute Tox. 2 Inhalation - Acute Tox. 3 Dermal - Acute Tox. 3 Oral - STOT RE 1 Oral
• Code de la classe de stockage: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges