D7408

2′,5′-Dideoxyadenosine

≥95% (HPLC), solid

• Synonyme(s) : 2ʹ,5ʹ-dd-Ado, NSC 95943
• Formule empirique (notation de Hill): C₁₀H₁₃N₅O₂
• Numéro CAS: 6698-26-6
• Poids moléculaire : 235.24
• Numéro MDL: MFCD00210904
• Code UNSPSC : 41106305
• ID de substance PubChem : 24894132
• Nomenclature NACRES : NA.77

Propriétés

• Niveau de qualité: 100
• Pureté: ≥95% (HPLC)
• Forme: solid
• Couleur: white
• Solubilité: DMSO: soluble
• Température de stockage: −20°C
• Chaîne SMILES: C[C@H]1O[C@H](C[C@@H]1O)n2cnc3c(N)ncnc23
• InChI: 1S/C10H13N5O2/c1-5-6(16)2-7(17-5)15-4-14-8-9(11)12-3-13-10(8)15/h3-7,16H,2H2,1H3,(H2,11,12,13)/t5-,6+,7-/m1/s1
• Clé InChI: FFHPXOJTVQDVMO-DSYKOEDSSA-N
• Informations sur le gène: rat ... Adcy2(81636)

Description

Application

2′,5′-Dideoxyadenosine has been used to elucidate the mechanism of diligustilide (DLG). It has also been used to inhibit adenylate cyclase (AC).

Actions biochimiques/physiologiques

Cell-permeable adenylyl cyclase inhibitor. IC₅₀ = 2.7 μM in detergent-dispersed rat brain preparations.

Caractéristiques et avantages

This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the Adenylyl cyclases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Reconstitution

Store at −20 °C after reconstitution.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)