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T1810000

Tranexamic acid

European Pharmacopoeia (EP) Reference Standard

Synonyme(s) :

trans-4-(Aminomethyl)cyclohexanecarboxylic acid, AMCA, AMCHA, HAKU, TAMCHA, Tranexamic acid

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About This Item

Formule linéaire :
H2NCH2C6H10CO2H
Numéro CAS:
1197-18-8
Poids moléculaire :
157.21
Numéro Beilstein :
2207452
Numéro MDL:
MFCD00001466
Code UNSPSC :
41116107
ID de substance PubChem :
329826687
Nomenclature NACRES :
NA.24

Qualité

pharmaceutical primary standard

Famille d'API

tranexamic acid

Fabricant/nom de marque

EDQM

Pf

>300 °C (lit.)

Application(s)

pharmaceutical (small molecule)

Format

neat

Température de stockage

2-8°C

Chaîne SMILES 

NC[C@H]1CC[C@@H](CC1)C(O)=O

InChI

1S/C8H15NO2/c9-5-6-1-3-7(4-2-6)8(10)11/h6-7H,1-5,9H2,(H,10,11)/t6-,7-

Clé InChI

GYDJEQRTZSCIOI-LJGSYFOKSA-N

Informations sur le gène

human ... PLG(5340)

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Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Tranexamic acid EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Conditionnement

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Autres remarques

Sales restrictions may apply.

Pictogrammes

Exclamation mark
GHS07

Mention d'avertissement

Warning

Mentions de danger

H315,H319,H335

Classification des risques

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organes cibles

Respiratory system

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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Certificats d'analyse (COA)

Lot/Batch Number

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Sattar Alshryda et al.
The Journal of bone and joint surgery. American volume, 95(21), 1969-1974 (2013-11-08)
Approximately one-third of patients undergoing total hip replacement surgery require one to three units of blood postoperatively. Tranexamic acid is a synthetic antifibrinolytic agent that has been successfully used intravenously to control bleeding after total hip replacement. A topical application
Sattar Alshryda et al.
The Journal of bone and joint surgery. American volume, 95(21), 1961-1968 (2013-11-08)
Approximately one-third of patients undergoing total knee replacement require one to three units of blood postoperatively. Tranexamic acid (TXA) is a synthetic antifibrinolytic agent that has been successfully used intravenously to stop bleeding after total knee replacement. A topical application
S Grassin-Delyle et al.
British journal of anaesthesia, 111(6), 916-924 (2013-07-25)
Interest in antifibrinolytic tranexamic acid (TA) has grown since the widespread removal of aprotinin, but its dosing during cardiac surgery is still debated. The objectives of this study were to investigate the population pharmacokinetics (PK) of TA given with either
Kristen A Matteson et al.
Obstetrics and gynecology, 121(3), 632-643 (2013-05-03)
To compare the effectiveness of nonsurgical abnormal uterine bleeding treatments for bleeding control, quality of life (QOL), pain, sexual health, patient satisfaction, additional treatments needed, and adverse events. MEDLINE, Cochrane databases, and Clinicaltrials.gov were searched from inception to May 2012.
Case scenario: management of trauma-induced coagulopathy in a severe blunt trauma patient.
Jean-Stephane David et al.
Anesthesiology, 119(1), 191-200 (2013-03-22)
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