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Key Documents

R0950000

Rifamycin S

European Pharmacopoeia (EP) Reference Standard

Synonyme(s) :

1,4-Dideoxy-1,4-dihydro-1,4-dioxorifamycin

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About This Item

Formule empirique (notation de Hill):
C37H45NO12
Numéro CAS:
13553-79-2
Poids moléculaire :
695.75
Code UNSPSC :
41116107
Nomenclature NACRES :
NA.24

Qualité

pharmaceutical primary standard

Famille d'API

rifamycin, rifampicin

Fabricant/nom de marque

EDQM

Application(s)

pharmaceutical (small molecule)

Format

neat

Température de stockage

2-8°C

InChI

1S/C37H45NO12/c1-16-11-10-12-17(2)36(46)38-23-15-24(40)26-27(32(23)44)31(43)21(6)34-28(26)35(45)37(8,50-34)48-14-13-25(47-9)18(3)33(49-22(7)39)20(5)30(42)19(4)29(16)41/h10-16,18-20,25,29-30,33,41-43H,1-9H3,(H,38,46)/b11-10+,14-13+,17-12-/t16-,18+,19+,20+,25-,29-,30+,33+,37-/m0/s1

Clé InChI

BTVYFIMKUHNOBZ-ODRIEIDWSA-N

Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Rifamycin S EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Conditionnement

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Autres remarques

Sales restrictions may apply.

Produit(s) apparenté(s)

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Description
Tarif

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Consulter la Bibliothèque de documents

Ming Chen et al.
The Journal of organic chemistry, 78(1), 3-8 (2012-06-19)
Syntheses of the C(15)-C(27) fragments of chaxamycins A/D, rifamycin S, and the C(12)-C(24) fragment of salinisporamycin have been accomplished in 10 steps from commercially available starting materials. Three crotylboron reagents were utilized to construct the seven contiguous stereocenters in these
U C Banerjee
Biomaterials, artificial cells, and immobilization biotechnology : official journal of the International Society for Artificial Cells and Immobilization Biotechnology, 21(5), 675-683 (1993-01-01)
Rifamycin oxidase of Curvularia lunata was immobilized on alginate gel. The pH and temperature optima of the immobilized enzyme preparation were 6.5 and 50 degrees C, respectively. Transformation reaction was carried out with the immobilized enzyme preparation. It took 8
Molecular structure and conformation of rifamycin S, a potent inhibitor of DNA-dependent RNA polymerase.
S K Arora et al.
The Journal of antibiotics, 45(3), 428-431 (1992-03-01)
S BouzBouz et al.
Organic letters, 3(25), 3995-3998 (2001-12-12)
[reaction: see text] An efficient, simple method has been developed for the stereocontrolled synthesis of polypropionate stereopentads in high enantio- and diastereomeric purities.
O Ghisalba et al.
The Journal of antibiotics, 35(1), 74-80 (1982-01-01)
The transformation of rifamycin S into rifamycins B and L was reinvestigated in order to establish more detailed pathways. Our results exclude rifamycin O as a common progenitor in the biosyntheses of rifamycins B and L. Rifamycins B and L
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