10982962001
Roche
N-Acetyl-β-D-Glucosaminidase Standard (NAG Standard)
from beef kidney
Synonyme(s) :
NAG standard
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About This Item
Code UNSPSC :
12352204
Produits recommandés
Source biologique
bovine kidney
Niveau de qualité
Forme
lyophilized
Activité spécifique
~20 mU/mL
Conditionnement
pkg of 5 × 3 mL (5 x 400 μg)
Fabricant/nom de marque
Roche
Technique(s)
activity assay: suitable
Couleur
white to light yellow
Solubilité
water: soluble
Application(s)
life science and biopharma
Température de stockage
20-25°C
Description générale
Standard for the determination of NAG activity in urine research samples with the aid of the Test-Combination N-acetyl-β-D-glucosaminidase.
N-Acetyl-β-D-Glucosaminidase is a high molecular weight lysosomal enzyme existing as two isofomrs, Isoenzyme-A and Isoenzyme-B. It is present in human kidney. It has high molecular weight. It is highly active in renal proximal tubular cells. It has been reported that overexpressed urine-NAG reflects the proximal tubular dysfunction of the kidney.
N-Acetyl-β-D-Glucosaminidase is a high molecular weight lysosomal enzyme existing as two isofomrs, Isoenzyme-A and Isoenzyme-B. It is present in human kidney. It has high molecular weight. It is highly active in renal proximal tubular cells. It has been reported that overexpressed urine-NAG reflects the proximal tubular dysfunction of the kidney.
Application
The NAG standard is used for the determination of NAG activity in urine in life science research applications, with the aid of N-acetyl-β-D-glucosaminidase. It can be used in automatic analyzers.
Définition de l'unité
Volume Activity: The activity of the NAG standard is approximately 20 mU N-acetyl-β-D-glucosaminidase from beef kidney per ml. For exact values, see data printed on the label.
Notes préparatoires
Storage conditions (working solution): 2 to 8 °C
Stability of the standard solution
The solution is stable for at least 1 month stored at 2 to 8 °C, protected from light.
Stability of the standard solution
The solution is stable for at least 1 month stored at 2 to 8 °C, protected from light.
Reconstitution
Preparation of the standard solution
Dissolve contents of one bottle with 3 ml double distilled water, close bottle and wait for 5 minutes. Dissolve contents completely by gentle swirling. Avoid creating foam.
Dissolve contents of one bottle with 3 ml double distilled water, close bottle and wait for 5 minutes. Dissolve contents completely by gentle swirling. Avoid creating foam.
Stockage et stabilité
Keep protected from light.
Autres remarques
For life science research only. Not for use in diagnostic procedures.
Mentions de danger
Conseils de prudence
Classification des risques
Aquatic Chronic 3
Code de la classe de stockage
11 - Combustible Solids
Classe de danger pour l'eau (WGK)
WGK 3
Point d'éclair (°F)
does not flash
Point d'éclair (°C)
does not flash
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Les clients ont également consulté
Ravi Babu Kalahasthi et al.
Journal of occupational medicine and toxicology (London, England), 2, 5-5 (2007-07-31)
The present study was carried out to determine the effect of cadmium exposure on Urinary N-acetyl-beta -D-glucosaminidase and its isoenzymes A and B in workers exposed at cadmium plating. 50 subjects using cadmium during cadmium plating formed the study group.
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