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T0178

Sigma-Aldrich

apo-Transferrin bovine

≥98%

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About This Item

CAS-Nummer:
11096-37-0
EG-Nummer:
234-318-8
MDL-Nummer:
MFCD00130536
UNSPSC-Code:
12352202
NACRES:
NA.61

Biologische Quelle

bovine

Assay

≥98%

Form

powder

Methode(n)

cell culture | mammalian: suitable

Löslichkeit

H2O: 20 mg/mL

UniProt-Hinterlegungsnummer

Q29443

Lagertemp.

2-8°C

Angaben zum Gen

bovine ... TF(280705)

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Anwendung

All cells require iron for the proper uptake of oxygen from their environment. Transferrin, a protein isolated from serum, causes the uptake and transport of iron from culture medium to the cells. This allows proper oxygen uptake and also stimulates growth-related enzyme activity. Iron-saturated transferrin (holo transferrin) is continually recycled after releasing iron and becomes iron-deficient transferrin (apo-transferrin). Choosing which form to use depends upon the culture conditions. In media such as Dulbecco′s Modified Eagle′s Medium/Ham′s Nutrient Mixture F12 (DMEM/F12) that contain high levels of iron salt, using apo-transferrin is preferred.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)

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Sandeep Kumar et al.
The journal of physical chemistry. B, 121(37), 8669-8683 (2017-08-25)
The macromolecular crowding influences the structural stability and functional properties of transferrin (Tf). The equilibrium as well as kinetic studies of Tf at different concentrations of crowding agents (dextran 40, dextran 70, and ficoll 70) and at a fixed concentration
Min Lin et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 36(40), 10376-10391 (2016-10-07)
Methamphetamine (METH) is a substrate for the dopamine transporter that increases extracellular dopamine levels by competing with dopamine uptake and increasing reverse transport of dopamine via the transporter. METH has also been shown to alter the excitability of dopamine neurons.
J L Hayworth et al.
Clinical and experimental immunology, 157(1), 60-70 (2009-08-08)
Staphylococcal enterotoxin B (SEB) is a pyrogenic exotoxin and a potent superantigen which causes massive T cell activation and cytokine secretion, leading to profound immunosuppression and morbidity. The inhibition of SEB-induced responses is thus considered a goal in the management

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