SML3844

Iberin

≥97% (NMR)

• Synonym(e): 1-Isothiocyanato-3-(methylsulfinyl)propane, 3-Methylsulfinylpropyl isothiocyanate, NSC 321801
• Empirische Formel (Hill-System): C₅H₉NOS₂
• CAS-Nummer: 505-44-2
• Molekulargewicht: 163.26
• MDL-Nummer: MFCD25977777
• UNSPSC-Code: 51111800
• UNSPSC-Code: 12352200
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥97% (NMR)
• Form: liquid
• Farbe: colorless to yellow
• Lagertemp.: -10 to -25°C

Beschreibung

Biochem./physiol. Wirkung

Iberin is a natural isothiocyanates from cruciferous vegetables (cabbage, red cabbage, horseradish) that potently inhibits toll-like receptors (TLRs) signaling. Iberin covalently binds to TLR4 and TLR2, which inhibits TLR dimerization. Iberin exhibits potent antioxidant, anticancer, and antimicrobial activities. It is quorum-sensing inhibitor (QSI) of the bacterial pathogen Pseudomonas aeruginosa through downregulation of the Gac/Rsm QS network.

Sicherheitshinweise

• Piktogramme: GHS06,GHS09
• Signalwort: Danger
• H-Sätze: H301 + H311 + H331,H315,H319,H335,H410
• P-Sätze: P273 - P280 - P301 + P310 - P302 + P352 + P312 - P304 + P340 + P311 - P305 + P351 + P338
• Gefahreneinstufungen: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable