SML3571

GS-621763

≥98% (HPLC)

• Synonym(e): (2R,3R,4R,5R)-2-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-2-cyano-5-((isobutyryloxy)methyl)tetrahydrofuran-3,4-diyl bis(2-methylpropanoate)
• Empirische Formel (Hill-System): C₂₄H₃₁N₅O₇
• CAS-Nummer: 2647442-13-3
• Molekulargewicht: 501.53
• UNSPSC-Code: 51111800
• UNSPSC-Code: 12352200
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥98% (HPLC)
• Form: powder
• Farbe: white to beige
• Löslichkeit: DMSO: 2 mg/mL, clear
• Lagertemp.: 2-8°C
• SMILES String: N#C[C@@]1(C2=CC=C3C(N)=NC=NN32)O[C@@H]([C@H]([C@H]1OC(C(C)C)=O)OC(C(C)C)=O)COC(C(C)C)=O

Beschreibung

Biochem./physiol. Wirkung

GS-621763 is an orally bioavailable analog of remdesivir, which is efficiently converted in plasma to active metabolite GS-441524, or in lungs to the bioactive triphosphate GS-443902. GS-621763 effectively reduces SARS-CoV-2 burden to near-undetectable levels in ferrets.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable