SML0978

ML291

≥98% (HPLC)

• Synonym(e): CID52940465, N-(4-((4-Chloropiperidin-1-yl)sulfonyl)phenyl)-5-nitrofuran-2-carboxamide, SID134228465
• Empirische Formel (Hill-System): C₁₆H₁₆ClN₃O₆S
• CAS-Nummer: 1523437-16-2
• Molekulargewicht: 413.83
• UNSPSC-Code: 12352200
• NACRES: NA.77

Eigenschaften

• Assay: ≥98% (HPLC)
• Form: powder
• Farbe: white to beige
• Löslichkeit: DMSO: 20 mg/mL, clear
• Lagertemp.: 2-8°C

Beschreibung

Biochem./physiol. Wirkung

ML291 specifically activates the apoptotic arm of the cellular unfolded protein response ( UPR) EC₅₀ = 762 nM) with 105-fold selectivity over activation of the adaptive UPR pathway. ML291 induces apoptosis in wild-type mouse embryonic fibroblasts (MEFs), but not in CHOP KO MEFs.

Leistungsmerkmale und Vorteile

This compound is a featured product for Apoptosis research. Click here to discover more featured Apoptosis products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable