R4632

Retinylacetat

synthetic, crystalline solid or supercooled liquid

• Synonym(e): Retinolacetat, Vitamin A-acetat
• Empirische Formel (Hill-System): C₂₂H₃₂O₂
• CAS-Nummer: 127-47-9
• Molekulargewicht: 328.49
• Beilstein: 1915439
• EG-Nummer: 204-844-2
• MDL-Nummer: MFCD00019413
• UNSPSC-Code: 12352205
• eCl@ss: 34058009
• PubChem Substanz-ID: 57654592
• NACRES: NA.79

Eigenschaften

• Biologische Quelle: synthetic
• Qualitätsniveau: 300
• Assay: ≥90% (HPLC)
• Form: crystalline solid or supercooled liquid
• Wirksamkeit: 2,600,000-2,940,000 I.U. per g
• Farbe: light yellow to dark yellow
• mp (Schmelzpunkt): 57-58 °C; ~58 °C (lit.)
• Lagertemp.: −20°C
• SMILES String: CC1=C(/C=C/C(C)=C/C=C/C(C)=C/COC(C)=O)C(C)(C)CCC1
• InChI: 1S/C22H32O2/c1-17(9-7-10-18(2)14-16-24-20(4)23)12-13-21-19(3)11-8-15-22(21,5)6/h7,9-10,12-14H,8,11,15-16H2,1-6H3/b10-7+,13-12+,17-9+,18-14+
• InChIKey: QGNJRVVDBSJHIZ-QHLGVNSISA-N

Beschreibung

Allgemeine Beschreibung

Vitamin A usually occurs in food as retinyl esters, which are the pre-formed sources of vitamin A. Retinyl acetate exists as yellow crystals and is insoluble in water. It is soluble in ethanol and oils.

Anwendung

Retinyl acetate has been used:

• to study its effects on cochlear development in mice
• as a component of an internal standard to quantify antioxidants in yolk
• as an internal standard to determine serum retinol concentration

Biochem./physiol. Wirkung

Retinal, retinol and retinoic acid are the aldehyde, alcohol and acid forms of vitamin A. The retinoids exist as many geometric isomers due to the unsaturated bonds in the aliphatic chain.
Retinoids also exist as retinyl esters such as retinyl propionate, retinyl acetate and retinyl palmitate. Retinyl esters provide pools of vitamin A that are converted into retinol and other retinoids as needed. Retinyl acetate is used in a wide range of biological applications.

Physikalische Form

Packaged as a melt and may exist as a crystalline solid or a supercooled viscous liquid

Hinweis zur Analyse

Activity based on HPLC comparison to USP standard.

Sicherheitshinweise

• Piktogramme: GHS08
• Signalwort: Danger
• H-Sätze: H360D,H413
• P-Sätze: P202 - P273 - P280 - P308 + P313 - P405 - P501
• Gefahreneinstufungen: Aquatic Chronic 4 - Repr. 1B
• Lagerklassenschlüssel: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 2
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type ABEK (EN14387) respirator filter