R1276

Reversin 121

≥97% (HPLC), powder

• Synonym(e): Boc-Asp(Obzl)-Lys(Z)-OtBu
• Empirische Formel (Hill-System): C₃₄H₄₇N₃O₉
• CAS-Nummer: 174630-04-7
• Molekulargewicht: 641.75
• MDL-Nummer: MFCD03788012
• UNSPSC-Code: 12161501
• PubChem Substanz-ID: 329823998
• NACRES: NA.47

Eigenschaften

• Assay: ≥97% (HPLC)
• Form: powder
• Farbe: white
• mp (Schmelzpunkt): 200 °C
• Löslichkeit: DMSO or ethanol: soluble
• Lagertemp.: −20°C
• SMILES String: CC(C)(C)OC(=O)N[C@@H](CC(=O)OCc1ccccc1)C(=O)N[C@@H](CCCCNC(=O)OCc2ccccc2)C(=O)OC(C)(C)C
• InChI: 1S/C34H47N3O9/c1-33(2,3)45-30(40)26(19-13-14-20-35-31(41)44-23-25-17-11-8-12-18-25)36-29(39)27(37-32(42)46-34(4,5)6)21-28(38)43-22-24-15-9-7-10-16-24/h7-12,15-18,26-27H,13-14,19-23H2,1-6H3,(H,35,41)(H,36,39)(H,37,42)/t26-,27-/m0/s1
• InChIKey: SVNKEDMVAQBLLN-SVBPBHIXSA-N
• Angaben zum Gen: human ... GRIN2A(2903) ; mouse ... GRIN2A(14811) ; rat ... GRIN2A(24409)

Beschreibung

Allgemeine Beschreibung

Reversin 121 is an analog of reversin and a dipeptide derivative.

Anwendung

Reversin 121 has been used to determine the activity of P-glycoprotein in human retinal pigment epithelium.

Biochem./physiol. Wirkung

Peptide chemosensitizer, inhibitor of P-glycoprotein.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)