PZ0129

CP-380736

≥98% (HPLC)

• Synonym(e): 6,7-Bis(2-methoxyethoxy)-3,4-dihydroquinazolin-4-one, 6,7-Bis(2-methoxyethoxy)-4(3H)-quinazolinone, PF-00520893
• Empirische Formel (Hill-System): C₁₄H₁₈N₂O₅
• CAS-Nummer: 179688-29-0
• Molekulargewicht: 294.30
• MDL-Nummer: MFCD02678087
• UNSPSC-Code: 51111800
• PubChem Substanz-ID: 329823716
• NACRES: NA.77

Eigenschaften

• Assay: ≥98% (HPLC)
• Form: powder
• Farbe: off-white to light tan
• Löslichkeit: DMSO: ≥10 mg/mL
• Lagertemp.: room temp
• SMILES String: COCCOc1cc2N=CNC(=O)c2cc1OCCOC
• InChI: 1S/C14H18N2O5/c1-18-3-5-20-12-7-10-11(15-9-16-14(10)17)8-13(12)21-6-4-19-2/h7-9H,3-6H2,1-2H3,(H,15,16,17)
• InChIKey: PMQWTUWLIGJTQD-UHFFFAOYSA-N

Beschreibung

Biochem./physiol. Wirkung

CP-380736 is an inhibitor of the epidermal growth factor receptor (EGFR). EGFR is a tyrosine kinase that activates MAPK, JNK, and Akt pathways, and is an important mediator of several types of cancer, including lung cancer and glioblastoma multiforme.

Leistungsmerkmale und Vorteile

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Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable