P127

(+)-Pentazocine

solid

• Empirische Formel (Hill-System): C₁₉H₂₇NO
• CAS-Nummer: 7361-76-4
• Molekulargewicht: 285.42
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 24898179
• NACRES: NA.77

Eigenschaften

• Form: solid
• Qualitätsniveau: 100
• Optische Aktivität: [α]23/D +134.6°, c = 1 in chloroform(lit.)
• Arzneimittelkontrolle: USDEA Schedule IV; Home Office Schedule 3; stupéfiant (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada; psicótropo (Spain); Decreto Lei 15/93: Tabela IIC (Portugal)
• Farbe: white
• Ersteller: Sanofi Aventis
• SMILES String: [H][C@@]12Cc3ccc(O)cc3[C@@](C)(CCN1C\C=C(\C)C)[C@@H]2C
• InChI: 1S/C19H27NO/c1-13(2)7-9-20-10-8-19(4)14(3)18(20)11-15-5-6-16(21)12-17(15)19/h5-7,12,14,18,21H,8-11H2,1-4H3/t14-,18+,19+/m1/s1
• InChIKey: VOKSWYLNZZRQPF-CCKFTAQKSA-N
• Angaben zum Gen: human ... EBP(10682) ; rat ... Chrm1(25229) , Chrm2(81645) , Drd2(24318) , Oprm1(25601)

Beschreibung

Biochem./physiol. Wirkung

σ receptor agonist; active enantiomer of pentazocine.

Leistungsmerkmale und Vorteile

This compound was developed by Sanofi Aventis. To browse the list of other pharma-developed compounds, Approved Drugs, and Drug Candidates, click here.

Vorsicht

Photosensitive

Rekonstituierung

A 10 mM solution of (+)-pentazocine is prepared by warming 28.5 mg of (+)-pentazocine free base in 2 mL of 0.1N HCl with shaking or sonication. When all solids have dissolved, the solution is cooled to room temperature and diluted with 10 mL of pH 7 buffer. Solutions should be freshly prepared, since cooling below room temperature may result in precipitation.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H302 + H312 + H332
• P-Sätze: P261 - P264 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312
• Gefahreneinstufungen: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves