N7785

β-Nicotinamide adenine dinucleotide 2′-phosphate reduced Tetranatriumsalz

vial of 10 mg, ~95%

• Synonym(e): β-NADPH, 2′-NADPH, Coenzyme II reduced Tetranatriumsalz, Dihydronicotinamide adenine dinucleotide phosphate Tetranatriumsalz, NADPH Na₄, TPNH₂ Na₄, Triphosphopyridine nucleotide reduced Tetranatriumsalz
• Empirische Formel (Hill-System): C₂₁H₂₆N₇Na₄O₁₇P₃
• Molekulargewicht: 833.35
• EG-Nummer: 214-664-6
• MDL-Nummer: MFCD00036263
• UNSPSC-Code: 41106305
• PubChem Substanz-ID: 24897841
• NACRES: NA.51

Eigenschaften

• Assay: ~95%
• Qualitätsniveau: 200
• Form: powder
• Verpackung: vial of 10 mg
• InChI: 1S/C21H30N7O17P3.4Na/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(44-46(33,34)35)14(30)11(43-21)6-41-48(38,39)45-47(36,37)40-5-10-13(29)15(31)20(42-10)27-3-1-2-9(4-27)18(23)32;;;;/h1,3-4,7-8,10-11,13-16,20-21,29-31H,2,5-6H2,(H2,23,32)(H,36,37)(H,38,39)(H2,22,24,25)(H2,33,34,35);;;;/q;4*+1/p-4/t10-,11+,13-,14+,15-,16+,20-,21+;;;;/m0..../s1
• InChIKey: WYWWVJHQDVCHKF-MPUNMZHWSA-J

Beschreibung

Anwendung

β-Nicotinamide adenine dinucleotide 2′-phosphate (NADP+) and β-Nicotinamide adenine dinucleotide 2′-phosphate, reduced (NADPH) comprise a coenzyme redox pair (NADP+:NADPH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. The NADP+/NADPH redox pair facilitates electron transfer in anabolic reactions such as lipid and cholesterol biosynthesis and fatty acyl chain elongation. The NADP⁺/NADPH redox pair is used in a variety of antioxidation mechanism where it protects agains reactive oxidation species accumulation. NADPH is generated in vivio by the pentose phosphate pathway (PPP).

β-Nicotinamide adenine dinucleotide 2′-phosphate reduced tetrasodium salt has been used in the Griess reagent assay of culture medium to reduce nitrate to nitrite and in glutathione peroxidase assay.

Biochem./physiol. Wirkung

β-Nicotinamide adenine dinucleotide 2′-phosphate (NADP⁺) and β-Nicotinamide adenine dinucleotide 2′-phosphate, reduced (NADPH) comprise a coenzyme redox pair (NADP⁺:NADPH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. The NADP⁺/NADPH redox pair facilitates electron transfer in anabolic reactions such as lipid and cholesterol biosynthesis and fatty acyl chain elongation. The NADP⁺/NADPH redox pair is used in a variety of antioxidation mechanism where it protects agains reactive oxidation species accumulation. NADPH is generated in vivo by the pentose phosphate pathway (PPP).

Angaben zur Herstellung

Chemically reduced

Sonstige Hinweise

Packaged based on NADPH content as determined by UV-Vis.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)