N1016

Nimesulid

• Synonym(e): N-(4-Nitro-2-phenoxyphenyl)-methansulfonamid
• Empirische Formel (Hill-System): C₁₃H₁₂N₂O₅S
• CAS-Nummer: 51803-78-2
• Molekulargewicht: 308.31
• EG-Nummer: 257-431-4
• MDL-Nummer: MFCD00079470
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 24278583
• NACRES: NA.77

Eigenschaften

• Biologische Quelle: synthetic (organic)
• Assay: ≥98% (TLC)
• Form: powder
• Löslichkeit: ethanol: 50 mg/mL
• Lagertemp.: 2-8°C
• SMILES String: CS(NC1=C(OC2=CC=CC=C2)C=C([N+]([O-])=O)C=C1)(=O)=O
• InChI: 1S/C13H12N2O5S/c1-21(18,19)14-12-8-7-10(15(16)17)9-13(12)20-11-5-3-2-4-6-11/h2-9,14H,1H3
• InChIKey: HYWYRSMBCFDLJT-UHFFFAOYSA-N
• Angaben zum Gen: human ... ALB(213) , PTGS1(5742) , PTGS2(5743)

Beschreibung

Allgemeine Beschreibung

Nimesulide, a nonsteroidal anti-inflammatory drug (NSAID) belongs to the sulfonanilide class.

Anwendung

Nimesulide has been used as a component in the reaction mixture to determine the activity of cyclooxygenase (COX) in spleen of chickens.

Biochem./physiol. Wirkung

Nimesulide can be used as a substitute to other nonsteroidal anti-inflammatory drugs (NSAIDs) to treat pain and inflammation of osteoarthritis for a short period. It can perform anti-inflammatory, analgesic and antipyretic activities.

Sehr selektiver Cyclooxygenase-2-Hemmer.

Sicherheitshinweise

• Piktogramme: GHS06
• Signalwort: Danger
• H-Sätze: H301
• P-Sätze: P301 + P310
• Gefahreneinstufungen: Acute Tox. 3 Oral
• Lagerklassenschlüssel: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Faceshields, Gloves