G8032

Gelsolin from bovine plasma

≥95% (SDS-PAGE), lyophilized powder

• MDL-Nummer: MFCD00212964
• UNSPSC-Code: 12352204
• NACRES: NA.54

Eigenschaften

• Assay: ≥95% (SDS-PAGE)
• Form: lyophilized powder
• Spezifische Aktivität: 20-100 units/mg protein
• Mol-Gew.: 74 kDa
• Zusammensetzung: Protein, ≤10%
• Löslichkeit: soluble 10 imidazole mg/mL
• UniProt-Hinterlegungsnummer: Q3SX14
• Lagertemp.: −20°C
• Angaben zum Gen: cow ... GSN(280810)

Beschreibung

Anwendung

Gelsolin from bovine plasma was used in actin assembly assays.

Biochem./physiol. Wirkung

Gelsolin is an actin-binding protein that regulates the assembly and disassembly of actin filaments.

Gelsolin is an actin-severing protein found in mammalian cells and blood plasma. Exhibits tumor suppressor activity in several cancer cell lines and in nude mice.

Verpackung

Package size based on protein content

Einheitendefinition

One unit will reduce viscosity difference between actin solution and buffer by 50% in a 1 mL mixture containing 1-2mg F-actin, 0.15 M KCl, 20 mM Tris, pH 7.6, 0.2 mM CaCl₂, 0.2 mM ATP, and 1 mM DTT at 28 °C.

Physikalische Form

Lyophilized powder containing NaCl, Tris buffer salt, and EGTA

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H315,H319,H335
• P-Sätze: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves