AV03050

Anti-CDK8 antibody produced in rabbit

IgG fraction of antiserum

• Synonym(e): Anti-Cyclin-dependent kinase 8
• MDL-Nummer: MFCD02262687
• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100
• Konjugat: unconjugated
• Antikörperform: IgG fraction of antiserum
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: buffered aqueous solution
• Mol-Gew.: 53 kDa
• Speziesreaktivität: rabbit, bovine, dog, human, mouse, pig, horse
• Konzentration: 0.5 mg - 1 mg/mL
• Methode(n): western blot: suitable
• NCBI-Hinterlegungsnummer: NP_001251
• UniProt-Hinterlegungsnummer: P49336
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Angaben zum Gen: human ... CDK8(1024)

Beschreibung

Immunogen

Synthetic peptide directed towards the C terminal region of human CDK8

Anwendung

Anti-CDK8 antibody produced in rabbit is suitable for western blotting at a concentration of 1.25 μg/ml.

Biochem./physiol. Wirkung

CDK8 is a regulator of transcription in a multisubunit complex with TFIIH and TEF-β. It exerts positive and negative effects on transcription and is involved signaling that controls nutrient sensing and cell differentiation. CDK8 phosphorylates the regulatory serine residue of STAT1 and mediates JAK-STAT1 signaling.

Sequenz

Synthetic peptide located within the following region: GLIMTSDYQRSNPHAAYPNPGPSTSQPQSSMGYSATSQQPPQYSHQTHRY

Physikalische Form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable